Control of an Intermittent Outbreak Caused by an Emerging Pandrug-Resistant Acinetobacter baumannii Clone ST457 in a Tertiary Hospital

Zhang, Chuqiu1,2; Xu, Tingting1,2; Ji, Yang1,2; Zheng, Wenping2,3; Wu, Jingsong2,4; Lu, Yuemei2,4; Li, Huiping1,2; Chen, Rongchang1,2; Qiu, Chen1,2; Zhou, Kai1,2

2021-12-01

10.1097/IM9.0000000000000066

INFECTIOUS MICROBES & DISEASES   影响因子和分区

2641-5917

Acinetobacter baumannii is a frequent cause of nosocomial infections. Here we report an intermittent outbreak caused by the emerging carbapenem-resistant A. baumannii (CRAB) clone ST457 and assess the effectiveness of patient screening for outbreak control. CRAB isolates were collected from 74 patients admitted to the respiratory intensive care unit of a tertiary hospital between May 2018 and March 2019. Fourteen CRAB isolates were assigned to ST457, and 13 belonged to an outbreak clone, as determined by phylogenomic analysis. Strict patient screening was started at the respiratory intensive care unit on May 2019, through which a ST457-positive patient transferred from the intensive care unit was detected. No positive patients were detected within 3 months onwards. The results of this study highlight the importance of rigorous infection prevention and control measures, combined with patient screening, in controlling the CRAB outbreak.

Acinetobacter baumannii carbapenem resistance nosocomial outbreak respiratory intensive care unit ST457

ESCI

英语

通讯

National Key Research and Development Program of China[2017YFC1200200] ; Major Infectious Diseases Such as AIDS and Viral Hepatitis Prevention and Control Technology Major Projects[2018ZX10712-001] ; National Natural Science Foundation of China[81902030] ; Shenzhen Basic Research Key projects[JCYJ20200109144220704] ; Shenzhen Basic Research projects[JCYJ20190807144409307]

Infectious Diseases ; Microbiology

Infectious Diseases ; Microbiology

WOS:000734395200007

LIPPINCOTT WILLIAMS & WILKINS

Web of Science

1.Jinan Univ, Shenzhen Inst Resp Dis, Clin Med Coll 2, Shenzhen Peoples Hosp, Shenzhen, Guangdong, Peoples R China
2.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen Peoples Hosp, Shenzhen, Guangdong, Peoples R China
3.Jinan Univ, Adm Dept Nosocomial Infect, Clin Med Coll 2, Shenzhen Peoples Hosp, Shenzhen, Guangdong, Peoples R China
4.Jinan Univ, Clin Lab, Clin Med Coll 2, Shenzhen Peoples Hosp, Shenzhen, Guangdong, Peoples R China

Zhang, Chuqiu,Xu, Tingting,Ji, Yang,et al. Control of an Intermittent Outbreak Caused by an Emerging Pandrug-Resistant Acinetobacter baumannii Clone ST457 in a Tertiary Hospital[J]. INFECTIOUS MICROBES & DISEASES,2021,3(4).

Zhang, Chuqiu.,Xu, Tingting.,Ji, Yang.,Zheng, Wenping.,Wu, Jingsong.,...&Zhou, Kai.(2021).Control of an Intermittent Outbreak Caused by an Emerging Pandrug-Resistant Acinetobacter baumannii Clone ST457 in a Tertiary Hospital.INFECTIOUS MICROBES & DISEASES,3(4).

Zhang, Chuqiu,et al."Control of an Intermittent Outbreak Caused by an Emerging Pandrug-Resistant Acinetobacter baumannii Clone ST457 in a Tertiary Hospital".INFECTIOUS MICROBES & DISEASES 3.4(2021).