南方科技大学知识苑(SUSTech KC): Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community

题名	Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community
作者	Cheng, Yingying 1; Yam, Joey Kuok Hoong 1; Cai, Zhao 1; Ding, Yichen 1; Zhang, Lian-Hui 2; Deng, Yinyue 3; Yang, Liang1,4,5
通讯作者	Cheng, Yingying; Yang, Liang
发表日期	2019-01-14
DOI	10.1038/s41522-018-0076-z
发表期刊	npj Biofilms and Microbiomes 影响因子和分区
ISSN	2055-5008
卷号	5
摘要	Pseudomonas aeruginosa tends to be among the dominant species in multi-species bacterial consortia in diverse environments. To understand P. aeruginosa's physiology and interactions with co-existing bacterial species in different conditions, we established physiologically reproducible 18 species communities, and found that P. aeruginosa dominated in mixed-species biofilm communities but not in planktonic communities. P. aeruginosa's H1 type VI secretion system was highly induced in mixed-species biofilm consortia, compared with its monospecies biofilm, which was further demonstrated to play a key role in P. aeruginosa's enhanced fitness over other bacterial species. In addition, the type IV pili and Psl exopolysaccharide were required for P. aeruginosa to compete with other bacterial species in the biofilm community. Our study showed that the physiology of P. aeruginosa is strongly affected by interspecies interactions, and both biofilm determinants and type VI secretion system contribute to higher P. aeruginosa's fitness over other species in complex biofilm communities.
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	通讯
资助项目	AcRF Tier 2 from Ministry of Education, Singapore[MOE2016-T2-1-010]
WOS研究方向	Biotechnology & Applied Microbiology ; Microbiology
WOS类目	Biotechnology & Applied Microbiology ; Microbiology
WOS记录号	WOS:000467563200001
出版者	SPRINGERNATURE
来源库	Web of Science
引用统计	被引频次[WOS]：35
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/26604
专题	南方科技大学医学院
作者单位	1.Nanyang Technol Univ, SCELSE, Singapore 637551, Singapore 2.South China Agr Univ, Integrat Microbiol Res Ctr, Guangdong Prov Key Lab Microbial Signals & Dis Co, Guangzhou 510642, Guangdong, Peoples R China 3.South China Agr Univ, Guangdong Innovat & Entrepreneurial Res Team Soci, Guangzhou 510642, Guangdong, Peoples R China 4.Nanyang Technol Univ, Sch Biol Sci, Singapore 637551, Singapore 5.Southern Univ Sci & Technol, Sch Med, Shenzhen 518055, Peoples R China
通讯作者单位	南方科技大学医学院
推荐引用方式 GB/T 7714	Cheng, Yingying,Yam, Joey Kuok Hoong,Cai, Zhao,et al. Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community[J]. npj Biofilms and Microbiomes,2019,5.
APA	Cheng, Yingying.,Yam, Joey Kuok Hoong.,Cai, Zhao.,Ding, Yichen.,Zhang, Lian-Hui.,...&Yang, Liang.(2019).Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community.npj Biofilms and Microbiomes,5.
MLA	Cheng, Yingying,et al."Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community".npj Biofilms and Microbiomes 5(2019).