Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: Combined computational predictions and experimental investigations

Zhang, Qian Ru1,4; Zhong, Zhang Feng1,6; Sang, Wei1; Xiong, Wei1; Tao, Hong Xun1; Zhao, Guan Ding1; Li, Zhi Xin1; Ma, Qiu Shuo1; Tse, Anfernee Kai Wing5; Hu, Yuan Jia1; Yu, Hua1,2,3; Wang, Yi Tao1

2019-01-10

10.1016/j.jep.2018.09.023

JOURNAL OF ETHNOPHARMACOLOGY   影响因子和分区

0378-8741

Ethnopharmacological relevance: Siegesbeckiae Herba (SH) is a traditional anti-rheumatic herbal medicine in China. The SH-derived product is the first licensed traditional herbal medicinal product for the management of rheumatism-induced joint and muscle pain in United Kingdom. The authenticated plant origins listed in the official Chinese Pharmacopeia for SH include Siegesbeckia orientalis L. (SO), S. pubescens Markino (SP) and S. glabrescens Markino (SG). Although the therapeutic effects of these SH species in treating rheumatoid arthritis (RA) are similar, their difference in chemical profiles suggested their anti-rheumatisms mechanisms and effects may be different.

Rheumatoid arthritis Siegesbeckiae Herba Computational prediction Similarity Difference

SCI

英语

其他

opening fund of the State Key Laboratory of Quality Research in Chinese Medicine of University of Macau[SKL-QRCM-2014-2016]

Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine

Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy

WOS:000452344800021

ELSEVIER IRELAND LTD

PHARMACOLOGY & TOXICOLOGY

Web of Science

1.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau, Peoples R China
2.HKBU Shenzhen Res Ctr, Shenzhen, Guangdong, Peoples R China
3.Hong Kong Baptist Univ, Sch Chinese Med, Kowloon Tong, Hong Kong, Peoples R China
4.Zunyi Med Univ, Sch Pharm, Zunyi, Guizhou, Peoples R China
5.Southern Univ Sci & Technol, Acad Adv Interdisciplinary Studies, Shenzhen, Guangdong, Peoples R China
6.Guangdong Med Univ, Guangdong Key Lab Res & Dev Nat Drugs, Zhanjiang, Peoples R China

Zhang, Qian Ru,Zhong, Zhang Feng,Sang, Wei,et al. Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: Combined computational predictions and experimental investigations[J]. JOURNAL OF ETHNOPHARMACOLOGY,2019,228:200-209.

Zhang, Qian Ru.,Zhong, Zhang Feng.,Sang, Wei.,Xiong, Wei.,Tao, Hong Xun.,...&Wang, Yi Tao.(2019).Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: Combined computational predictions and experimental investigations.JOURNAL OF ETHNOPHARMACOLOGY,228,200-209.

Zhang, Qian Ru,et al."Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: Combined computational predictions and experimental investigations".JOURNAL OF ETHNOPHARMACOLOGY 228(2019):200-209.