题名 | Concise Syntheses of Delta(12)-Prostaglandin J Natural Products via Stereoretentive Metathesis |
作者 | |
通讯作者 | Xu, Chen; Stoltz, Brian M.; Grubbs, Robert H. |
发表日期 | 2019-01-09
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DOI | |
发表期刊 | |
ISSN | 0002-7863
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卷号 | 141期号:1页码:154-158 |
摘要 | Delta(12)-Prostaglandin J family is recently discovered and has potent anticancer activity. Concise syntheses of four Delta(12)-prostaglandin J natural products (7-8 steps in the longest linear sequences) are reported, enabled by convergent stereoretentive cross-metathesis. Exceptional control of alkene geometry was achieved through stereoretention. |
相关链接 | [来源记录] |
收录类别 | |
语种 | 英语
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重要成果 | NI论文
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学校署名 | 通讯
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资助项目 | NSF[CHE 150216]
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WOS研究方向 | Chemistry
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WOS类目 | Chemistry, Multidisciplinary
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WOS记录号 | WOS:000455561800030
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出版者 | |
EI入藏号 | 20185206290655
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EI主题词 | Synthesis (chemical)
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EI分类号 | Chemistry:801
; Chemical Reactions:802.2
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来源库 | Web of Science
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引用统计 |
被引频次[WOS]:33
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成果类型 | 期刊论文 |
条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/26611 |
专题 | 深圳格拉布斯研究院 理学院_化学系 |
作者单位 | 1.CALTECH, Div Chem & Chem Engn, Arnold & Mabel Beckman Lab Chem Synth, Pasadena, CA 91125 USA 2.Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen 518000, Guangdong, Peoples R China 3.Southern Univ Sci & Technol, Dept Chem, Shenzhen 518000, Guangdong, Peoples R China |
通讯作者单位 | 深圳格拉布斯研究院; 化学系 |
推荐引用方式 GB/T 7714 |
Li, Jiaming,Ahmed, Tonia S.,Xu, Chen,et al. Concise Syntheses of Delta(12)-Prostaglandin J Natural Products via Stereoretentive Metathesis[J]. Journal of the American Chemical Society,2019,141(1):154-158.
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APA |
Li, Jiaming,Ahmed, Tonia S.,Xu, Chen,Stoltz, Brian M.,&Grubbs, Robert H..(2019).Concise Syntheses of Delta(12)-Prostaglandin J Natural Products via Stereoretentive Metathesis.Journal of the American Chemical Society,141(1),154-158.
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MLA |
Li, Jiaming,et al."Concise Syntheses of Delta(12)-Prostaglandin J Natural Products via Stereoretentive Metathesis".Journal of the American Chemical Society 141.1(2019):154-158.
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条目包含的文件 | 条目无相关文件。 |
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