| 题名 | Enantioselective and Diastereoselective Ir-Catalyzed Hydrogenation of alpha-Substituted beta-Ketoesters via Dynamic Kinetic Resolution |
| 作者 | |
| 通讯作者 | Wen, Jialin; Yin, Qin; Zhang, Xumu |
| 发表日期 | 2018-04-06
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| DOI | |
| 发表期刊 | |
| ISSN | 1523-7060
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| EISSN | 1523-7052
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| 卷号 | 20期号:7页码:1888-1892 |
| 摘要 | An iridium/f-amphol catalytic system for the enantioselective hydrogenation of alpha-substituted beta-ketoesters via dynamic kinetic resolution is reported. The desired anti products were obtained in high yields (up to 98%) with good diastereoselectivity (up to 96:4 diastereometic ratio (dr)) and excellent enantioselectivity (up to >99% enantiomeric excess (ee)). A catalytic model is proposed to explain the stereoselectivity. |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
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| 重要成果 | NI期刊
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| 学校署名 | 第一
; 通讯
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| 资助项目 | Shenzhen Research Grants[JSGG20160608140847864]
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| WOS研究方向 | Chemistry
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| WOS类目 | Chemistry, Organic
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| WOS记录号 | WOS:000429886900046
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| 出版者 | |
| ESI学科分类 | CHEMISTRY
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| 来源库 | Web of Science
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| 引用统计 |
被引频次[WOS]：37
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| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/27833 |
| 专题 | 理学院_化学系 前沿与交叉科学研究院 |
| 作者单位 | 1.Southern Univ Sci & Technol, Dept Chem, 1088 Xueyuan Rd, Shenzhen 518055, Guangdong, Peoples R China 2.Southern Univ Sci & Technol, Acad Adv Interdisciplinary Studies, 1088 Xueyuan Rd, Shenzhen 518055, Guangdong, Peoples R China |
| 第一作者单位 | 化学系 |
| 通讯作者单位 | 化学系; 前沿与交叉科学研究院 |
| 第一作者的第一单位 | 化学系 |
| 推荐引用方式 GB/T 7714 |
Gu, Guoxian,Lu, Jiaxiang,Yu, Ouran,et al. Enantioselective and Diastereoselective Ir-Catalyzed Hydrogenation of alpha-Substituted beta-Ketoesters via Dynamic Kinetic Resolution[J]. ORGANIC LETTERS,2018,20(7):1888-1892.
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| APA |
Gu, Guoxian,Lu, Jiaxiang,Yu, Ouran,Wen, Jialin,Yin, Qin,&Zhang, Xumu.(2018).Enantioselective and Diastereoselective Ir-Catalyzed Hydrogenation of alpha-Substituted beta-Ketoesters via Dynamic Kinetic Resolution.ORGANIC LETTERS,20(7),1888-1892.
|
| MLA |
Gu, Guoxian,et al."Enantioselective and Diastereoselective Ir-Catalyzed Hydrogenation of alpha-Substituted beta-Ketoesters via Dynamic Kinetic Resolution".ORGANIC LETTERS 20.7(2018):1888-1892.
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| 条目包含的文件 | 条目无相关文件。 | |||||
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