题名 | The Central Role of the Ubiquitin–Proteasome System in EBV-Mediated Oncogenesis |
作者 | |
通讯作者 | Robertson,Erle S. |
发表日期 | 2022-02-01
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DOI | |
发表期刊 | |
EISSN | 2072-6694
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卷号 | 14期号:3 |
摘要 | Deregulation of the ubiquitin–proteasome system (UPS) plays a critical role in the development of numerous human cancers. Epstein–Barr virus (EBV), the first known human tumor virus, has evolved distinct molecular mechanisms to manipulate the ubiquitin–proteasome system, facilitate its successful infection, and drive opportunistic cancers. The interactions of EBV antigens with the ubiquitin–proteasome system can lead to oncogenesis through the targeting of cellular factors involved in proliferation. Recent studies highlight the central role of the ubiquitin–proteasome system in EBV infection. This review will summarize the versatile strategies in EBV-mediated oncogenesis that contribute to the development of specific therapeutic approaches to treat EBV-associated malignancies. |
关键词 | |
相关链接 | [Scopus记录] |
收录类别 | |
语种 | 英语
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学校署名 | 第一
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WOS研究方向 | Oncology
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WOS类目 | Oncology
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WOS记录号 | WOS:000756134300001
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出版者 | |
Scopus记录号 | 2-s2.0-85123314120
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来源库 | Scopus
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引用统计 |
被引频次[WOS]:10
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成果类型 | 期刊论文 |
条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/278359 |
专题 | 南方科技大学医学院_公共卫生及应急管理学院 |
作者单位 | 1.School of Public Health and Emergency Management,Southern University of Science and Technology,Shenzhen,518055,China 2.Departments of Otorhinolaryngology-Head and Neck Surgery,and Microbiology,Abramson Cancer Center,Perelman School of Medicine at the University of Pennsylvania,Philadelphia,19104,United States |
第一作者单位 | 公共卫生及应急管理学院 |
第一作者的第一单位 | 公共卫生及应急管理学院 |
推荐引用方式 GB/T 7714 |
Pei,Yonggang,Robertson,Erle S.. The Central Role of the Ubiquitin–Proteasome System in EBV-Mediated Oncogenesis[J]. Cancers,2022,14(3).
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APA |
Pei,Yonggang,&Robertson,Erle S..(2022).The Central Role of the Ubiquitin–Proteasome System in EBV-Mediated Oncogenesis.Cancers,14(3).
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MLA |
Pei,Yonggang,et al."The Central Role of the Ubiquitin–Proteasome System in EBV-Mediated Oncogenesis".Cancers 14.3(2022).
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条目包含的文件 | ||||||
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