Therapeutic Considerations and Conjugated Polymer-Based Photosensitizers for Photodynamic Therapy

Meng, Zihui1; Hou, Weiying2; Zhou, Hua2; Zhou, Libo2; Chen, Haobin2; Wu, Changfeng3

2018-03

10.1002/marc.201700614

MACROMOLECULAR RAPID COMMUNICATIONS   影响因子和分区

1022-1336

1521-3927

Conjugated polymers have recently attracted a great deal of attention for applications in photodynamic therapy (PDT) because of their light-harvesting capability, efficient energy transfer, and singlet oxygen generation properties. This review describes recent advances in PDT development, including therapeutic mechanisms of PDT in cancer treatments, light excitation methods, and especially recent advances of conjugated polyelectrolytes and conjugated polymer nanoparticles as photosensitizers. The future direction on PDT and further development of conjugated polymer photosensitizers are discussed. The aim of this review is to stimulate innovative ideas to synthesize a new generation of conjugated polymer photosensitizers and promote their translation to clinical applications of PDT.

cancer conjugated polymers nanoparticles photodynamic therapy photosensitizers

SCI ; EI

英语

通讯

Shenzhen Science and Technology Innovation Commission[JCYJ20170307110157501]

Polymer Science

Polymer Science

WOS:000426647000003

WILEY-V C H VERLAG GMBH

20175104556968

Diseases ; Energy transfer ; Functional polymers ; Gas generators ; Nanoparticles ; Photodynamic therapy ; Photosensitizers ; Polyelectrolytes

Medicine and Pharmacology:461.6 ; Gas Fuels:522 ; Light/Optics:741.1 ; Nanotechnology:761 ; Polymeric Materials:815.1 ; Organic Polymers:815.1.1 ; Solid State Physics:933

CHEMISTRY

Web of Science

1.Jilin Univ, China Japan Union Hosp, Dept Hepatobiliary Pancreat Surg, Changchun 130033, Jilin, Peoples R China
2.Jilin Univ, State Key Lab Integrated Optoelect, Coll Elect Sci & Engn, Changchun 130012, Jilin, Peoples R China
3.Southern Univ Sci & Technol, Dept Biomed Engn, Shenzhen 518055, Guangdong, Peoples R China

Meng, Zihui,Hou, Weiying,Zhou, Hua,et al. Therapeutic Considerations and Conjugated Polymer-Based Photosensitizers for Photodynamic Therapy[J]. MACROMOLECULAR RAPID COMMUNICATIONS,2018,39(5).

Meng, Zihui,Hou, Weiying,Zhou, Hua,Zhou, Libo,Chen, Haobin,&Wu, Changfeng.(2018).Therapeutic Considerations and Conjugated Polymer-Based Photosensitizers for Photodynamic Therapy.MACROMOLECULAR RAPID COMMUNICATIONS,39(5).

Meng, Zihui,et al."Therapeutic Considerations and Conjugated Polymer-Based Photosensitizers for Photodynamic Therapy".MACROMOLECULAR RAPID COMMUNICATIONS 39.5(2018).