| 题名 | Novel Sulfolobus Virus with an Exceptional Capsid Architecture |
| 作者 | |
| 通讯作者 | Zhu, Ping; Huang, Li |
| 发表日期 | 2018-03
|
| DOI | |
| 发表期刊 | |
| ISSN | 0022-538X
|
| EISSN | 1098-5514
|
| 卷号 | 92期号:5 |
| 摘要 | A novel archaeal virus, denoted Sulfolobus ellipsoid virus 1 (SEV1), was isolated from an acidic hot spring in Costa Rica. The morphologically unique virion of SEV1 contains a protein capsid with 16 regularly spaced striations and an 11-nm-thick envelope. The capsid exhibits an unusual architecture in which the viral DNA, probably in the form of a nucleoprotein filament, wraps around the longitudinal axis of the virion in a plane to form a multilayered disk-like structure with a central hole, and 16 of these structures are stacked to generate a spool-like capsid. SEV1 harbors a linear double-stranded DNA genome of similar to 23 kb, which encodes 38 predicted open reading frames (ORFs). Among the few ORFs with a putative function is a gene encoding a protein-primed DNA polymerase. Sixfold symmetrical virus-associated pyramids (VAPs) appear on the surface of the SEV1-infected cells, which are ruptured to allow the formation of a hexagonal opening and subsequent release of the progeny virus particles. Notably, the SEV1 virions acquire the lipid membrane in the cytoplasm of the host cell. The lipid composition of the viral envelope correlates with that of the cell membrane. These results suggest the use of a unique mechanism by SEV1 in membrane biogenesis. |
| 关键词 | |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 学校署名 | 其他
|
| 资助项目 | NSFC[31425007]
; NSFC[31230018]
|
| WOS研究方向 | Virology
|
| WOS类目 | Virology
|
| WOS记录号 | WOS:000424744800007
|
| 出版者 | |
| ESI学科分类 | MICROBIOLOGY
|
| 来源库 | Web of Science
|
| 引用统计 |
被引频次[WOS]：13
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/27978 |
| 专题 | 工学院_海洋科学与工程系 |
| 作者单位 | 1.Chinese Acad Sci, Inst Microbiol, State Key Lab Microbial Resources, Beijing, Peoples R China 2.Chinese Acad Sci, Inst Biophys, CAS Ctr Excellence Biomacromol, Natl Lab Biomacromol, Beijing, Peoples R China 3.Tongji Univ, State Key Lab Marine Geol, Shanghai, Peoples R China 4.Univ Costa Rica, Ctr Res Cell & Mol Biol, San Jose, Costa Rica 5.South Univ Sci & Technol, Dept Ocean Sci & Engn, Shenzhen, Peoples R China 6.Univ Chinese Acad Sci, Coll Life Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 |
Wang, Haina,Guo, Zhenqian,Feng, Hongli,et al. Novel Sulfolobus Virus with an Exceptional Capsid Architecture[J]. JOURNAL OF VIROLOGY,2018,92(5).
|
| APA |
Wang, Haina.,Guo, Zhenqian.,Feng, Hongli.,Chen, Yufei.,Chen, Xiuqiang.,...&Huang, Li.(2018).Novel Sulfolobus Virus with an Exceptional Capsid Architecture.JOURNAL OF VIROLOGY,92(5).
|
| MLA |
Wang, Haina,et al."Novel Sulfolobus Virus with an Exceptional Capsid Architecture".JOURNAL OF VIROLOGY 92.5(2018).
|
| 条目包含的文件 | 条目无相关文件。 | |||||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
;
修改评论