Enantioselective synthesis of (-)- phaseic acid

Tu, Wentong1; Ning, Chengqing1,2; Xu, Jing1,2,3

2018-01

10.1039/c7qo00653e

Organic Chemistry Frontiers   影响因子和分区

2052-4129

Phaseic acid (PA) has long been considered an inactive oxidation catabolite of the essential plant hormone abscisic acid (ABA). However, a recent study disclosed that PA actually acts as an ABA receptor agonist and is capable of prolonging ABA effects in vivo. Here, we report a simple, enantioselective synthesis of (-)-phaseic acid. Key transformations of our strategy include a facile hydrozirconation reaction and a critical, Mn(III)-catalyzed allylic oxidation.

SCI ; EI ; IC ; CCR

英语

第一 ; 通讯

SUSTC Neural & Cognitive Sciences Research Center[Y01221001]

Chemistry

Chemistry, Organic

WOS:000418375600004

ROYAL SOC CHEMISTRY

20184806137390

Enantioselectivity ; Manganese compounds

Physical Chemistry:801.4

Web of Science

1.Southern Univ Sci & Technol, Dept Chem, Shenzhen, Guangdong, Peoples R China
2.SUSTech Acad Adv Interdisciplinary Studies, Shenzhen, Guangdong, Peoples R China
3.Grubbs Inst, Shenzhen, Guangdong, Peoples R China

Tu, Wentong,Ning, Chengqing,Xu, Jing. Enantioselective synthesis of (-)- phaseic acid[J]. Organic Chemistry Frontiers,2018,5(1):29-31.

Tu, Wentong,Ning, Chengqing,&Xu, Jing.(2018).Enantioselective synthesis of (-)- phaseic acid.Organic Chemistry Frontiers,5(1),29-31.

Tu, Wentong,et al."Enantioselective synthesis of (-)- phaseic acid".Organic Chemistry Frontiers 5.1(2018):29-31.