Non-Equilibrium Diffusion Controlled Ion-Selective Optical Sensor for Blood Potassium Determination

Du, Xinfeng; Xie, Xiaojiang

2017-10

10.1021/acssensors.7b00614

ACS Sensors   影响因子和分区

2379-3694

Blood electrolyte measurements play important roles in clinical diagnostics. Optical ion sensors as simple and elegant as a mercury thermometer are in high demand. We present here an analytical method to quantify potassium ions in undiluted human blood and plasma by measuring the distance or the rate of the color propagation. The sensor was composed of K+-selective nanospheres embedded in an agarose hydrogel where mass transport was diffusion controlled. The sensor's color-changing rate and the distance of color propagation depended linearly on the logarithm of K(+)activity. A theoretical model was established and fully supported the experimental findings. This work lays the foundation of a new family of optical ion sensors for direct determination of common blood electrolytes.

distance sensors blood electrolytes ion selective optodes hydrogels

SCI ; EI

英语

第一 ; 通讯

South University of Science and Technology of China[]

Chemistry ; Science & Technology - Other Topics

Chemistry, Multidisciplinary ; Chemistry, Analytical ; Nanoscience & Nanotechnology

WOS:000414238600005

AMER CHEMICAL SOC

20181705049203

Blood ; Color ; Electrolytes ; Hydrogels ; Potassium ; Sensors

Biological Materials and Tissue Engineering:461.2 ; Alkali Metals:549.1 ; Electric Batteries and Fuel Cells:702 ; Light/Optics:741.1 ; Chemical Agents and Basic Industrial Chemicals:803 ; Chemical Products Generally:804

Web of Science

Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China

Du, Xinfeng,Xie, Xiaojiang. Non-Equilibrium Diffusion Controlled Ion-Selective Optical Sensor for Blood Potassium Determination[J]. ACS Sensors,2017,2(10):1410-1414.

Du, Xinfeng,&Xie, Xiaojiang.(2017).Non-Equilibrium Diffusion Controlled Ion-Selective Optical Sensor for Blood Potassium Determination.ACS Sensors,2(10),1410-1414.

Du, Xinfeng,et al."Non-Equilibrium Diffusion Controlled Ion-Selective Optical Sensor for Blood Potassium Determination".ACS Sensors 2.10(2017):1410-1414.