Antibacterial activity, corrosion resistance and wear behavior of spark plasma sintered Ta-5Cu alloy for biomedical applications

Cui, Jing1; Zhao, Liang2; Zhu, Weiwei1; Wang, Bi1; Zhao, Cancan1; Fang, Liming2; Ren, Fuzeng1

2017-10

10.1016/j.jmbbm.2017.06.022

Journal of the Mechanical Behavior of Biomedical Materials   影响因子和分区

1751-6161

1878-0180

Tantalum has been widely used in orthopedic and dental implants. However, the major barrier to the extended use of such medical devices is the possibility of bacterial adhesion to the implant surface which will cause implant-associated infections. To solve this problem, bulk Ta-5Cu alloy has been fabricated by a combination of mechanical alloying and spark plasma sintering. The effect of the addition of Cu on the hardness, antibacterial activity, cytocompatibility, corrosion resistance and wear performance was systematically investigated. The sintered Ta-5Cu alloy shows enhanced antibacterial activity against E. Coll due to the sustained release of Cu ions. However, the addition of Cu would produce slight cytotoxicity and decrease corrosion resistance of Ta. Furthermore, pin-on-disk wear tests show that Ta-5Cu alloy has a much lower coefficient of friction but a higher wear rate and shows a distinct wear mode from that of Ta upon sliding against stainless steel 440 C. Wear induced plastic deformation leads to elongation of Ta and Cu grains along the sliding direction and nanolayered structures were observed upon approaching the sliding surface. The presence of hard oxides also shows a profound effect on the plastic flow of the base material and results in localized vortex patterns. The obtained results are expected to provide deep insights into the development of novel Ta-Cu alloy for biomedical applications.

Spark plasma sintering Ta-Cu alloy Antibacterial activity Corrosion Wear

SCI ; EI

英语

第一 ; 通讯

Special Funds for Fundamental Research of Strategic Emerging Industries of Shenzhen[JCYJ20150331101823688]

Engineering ; Materials Science

Engineering, Biomedical ; Materials Science, Biomaterials

WOS:000410253500034

ELSEVIER SCIENCE BV

20172603846385

Binary alloys ; Biomedical equipment ; Copper alloys ; Corrosion ; Corrosion resistance ; Dental alloys ; Dental prostheses ; Escherichia coli ; Friction ; Heavy ions ; Implants (surgical) ; Mechanical alloying ; Medical applications ; Spark plasma sintering ; Tantalum alloys ; Wear of materials ; Wear resistance

Biomedical Equipment:462 ; Metallurgy and Metallography:531 ; Metals Corrosion:539.1 ; Tantalum and Alloys:543.4 ; Copper Alloys:544.2 ; Physical Properties of Gases, Liquids and Solids:931.2

Web of Science

1.South Univ Sci & Technol China, Dept Mat Sci & Engn, Shenzhen 518055, Guangdong, Peoples R China
2.South China Univ Technol, Dept Polymer Sci & Engn, Sch Mat Sci & Engn, Guangzhou 510641, Guangdong, Peoples R China

Cui, Jing,Zhao, Liang,Zhu, Weiwei,et al. Antibacterial activity, corrosion resistance and wear behavior of spark plasma sintered Ta-5Cu alloy for biomedical applications[J]. Journal of the Mechanical Behavior of Biomedical Materials,2017,74:315-323.

Cui, Jing.,Zhao, Liang.,Zhu, Weiwei.,Wang, Bi.,Zhao, Cancan.,...&Ren, Fuzeng.(2017).Antibacterial activity, corrosion resistance and wear behavior of spark plasma sintered Ta-5Cu alloy for biomedical applications.Journal of the Mechanical Behavior of Biomedical Materials,74,315-323.

Cui, Jing,et al."Antibacterial activity, corrosion resistance and wear behavior of spark plasma sintered Ta-5Cu alloy for biomedical applications".Journal of the Mechanical Behavior of Biomedical Materials 74(2017):315-323.