南方科技大学知识苑(SUSTech KC): Echocardiographic study of myocardial work in patients with type 2 diabetes mellitus

题名	Echocardiographic study of myocardial work in patients with type 2 diabetes mellitus
作者	Liao, Lisi 1,2; Shi, Bobo 1,2; Ding, Zhimin 1,2; Chen, Lixin 1,2; Dong, Fajin 1,2; Li, Jian 1,2 ; Zhong, Yulin 1,2; Xu, Jinfeng 1,2
通讯作者	Xu, Jinfeng
发表日期	2022-02-17
DOI	10.1186/s12872-022-02482-3
发表期刊	BMC Cardiovascular Disorders 影响因子和分区
ISSN	1471-2261
卷号	22 期号:1
摘要	Background A noninvasive left ventricular (LV) pressure-strain loop (PSL) provides a new method to quantify myocardial work (MW) by combining global longitudinal strain (GLS) and LV pressure, which exerts potential advantages over traditional GLS. We studied the LV PSL and MW in patients with type 2 diabetes mellitus (T2DM). Methods This cross-sectional study included 201 subjects (54 healthy controls and 147 T2DM patients) who underwent complete two-dimensional echocardiography (2DE), including 2D speckle-tracking echocardiography (STE), as well as brachial artery pulse pressure measurement. The PSL was used to determine the global myocardial work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE) of all study participants. The association between T2DM and LV function was evaluated according to these MW indices. Results The GLS was significantly lower in the T2DM group than in the control group (P < 0.001), indicating that the LV myocardium had been damaged, although the LV ejection fraction (LVEF) was still normal. The GWI and GWE were decreased (P = 0.022) and the GWW was increased (P < 0.001) in diabetic patients compared with controls, but the GCW was comparable in the two groups (P = 0.160). In all diabetic patients, age, body mass index, systolic blood pressure, smoking history, and LVEF were correlated with GWI, GWW and GWE. Conclusions The use of LV PSL is a novel noninvasive technique that could help to depict the relationship between LV myocardial damage and MW in patients with T2DM.
关键词	Diabetes Echocardiography Left ventricular pressure-strain loop Myocardial work
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	第一 ; 通讯
资助项目	Natural Science Foundation of Shenzhen[JCYJ20190806151807192]
WOS研究方向	Cardiovascular System & Cardiology
WOS类目	Cardiac & Cardiovascular Systems
WOS记录号	WOS:000756855200001
出版者	BMC
来源库	Web of Science
引用统计	被引频次[WOS]：11
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/291057
专题	南方科技大学第一附属医院
作者单位	1.Southern Univ Sci & Technol, Affiliated Hosp 1, Dept Ultrasound, Shenzhen Med Ultrasound Engn Ctr,Shenzhen Peoples, 1017 Dongmen North Rd, Shenzhen 518020, Guangdong, Peoples R China 2.Jinan Univ, Shenzhen Peoples Hosp, Dept Ultrasound, Clin Coll 2, Shenzhen, Peoples R China
第一作者单位	南方科技大学第一附属医院
通讯作者单位	南方科技大学第一附属医院
第一作者的第一单位	南方科技大学第一附属医院
推荐引用方式 GB/T 7714	Liao, Lisi,Shi, Bobo,Ding, Zhimin,et al. Echocardiographic study of myocardial work in patients with type 2 diabetes mellitus[J]. BMC Cardiovascular Disorders,2022,22(1).
APA	Liao, Lisi.,Shi, Bobo.,Ding, Zhimin.,Chen, Lixin.,Dong, Fajin.,...&Xu, Jinfeng.(2022).Echocardiographic study of myocardial work in patients with type 2 diabetes mellitus.BMC Cardiovascular Disorders,22(1).
MLA	Liao, Lisi,et al."Echocardiographic study of myocardial work in patients with type 2 diabetes mellitus".BMC Cardiovascular Disorders 22.1(2022).