南方科技大学知识苑(SUSTech KC): Diversity-Oriented Synthesis of Fluoromethylated Arenes via Palladium-Catalyzed C-H Fluoromethylation of Aryl Iodides

题名	Diversity-Oriented Synthesis of Fluoromethylated Arenes via Palladium-Catalyzed C-H Fluoromethylation of Aryl Iodides
作者	Du, Yiming 1; Chen, Shuxin 1; Huang, Ao 1; Chen, Yihan 1; Liu, Yun-Lin 2; Song, Gaopeng 1; Tang, Ri-Yuan 1; Xu, Hanhong 3; Yao, Guangkai 3; Li, Zhaodong 1,3,4
通讯作者	Xu, Hanhong; Yao, Guangkai; Li, Zhaodong
发表日期	2022-02-18
DOI	10.1021/acs.orglett.1c04367
发表期刊	ORGANIC LETTERS 影响因子和分区
ISSN	1523-7060
EISSN	1523-7052
卷号	24 期号:6
摘要	Herein we report the first versatile and expeditious method for the site-selective C-H fluoromethylation of aryl iodides via Pd/norbornene cooperative catalysis, which could work as a robust toolbox for the diversity-oriented synthesis (DOS) of fluoromethylated arenes. This methodology features the use of the low-cost industrial raw material CH2IF as the fluoromethyl source, an excellent functional group tolerance, and a broad ipso termination scope and can be expanded to the late-stage modification of biorelevant molecules.
相关链接	[来源记录]
收录类别	SCI
语种	英语
重要成果	NI期刊
学校署名	通讯
资助项目	National Natural Science Foundation of China[22001080,82073722] ; Guangdong Provincial Key Laboratory of Catalysis[2020B121201002] ; Guangdong Basic and Applied Basic Research Foundation 2019[A1515011824] ; Science and Technology Program of Guangzhou[202102020321] ; Bureau of Guangdong Forestry[2020KJCX008] ; Guangdong Basic and Applied Basic Research Foundation 2021[A1515012433]
WOS研究方向	Chemistry
WOS类目	Chemistry, Organic
WOS记录号	WOS:000758180800015
出版者	AMER CHEMICAL SOC
ESI学科分类	CHEMISTRY
来源库	Web of Science
引用统计	被引频次[WOS]：14
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/296877
专题	南方科技大学
作者单位	1.South China Agr Univ, Coll Mat & Energy, Guangzhou 510642, Peoples R China 2.Guangzhou Univ, Sch Chem & Chem Engn, Guangzhou 510006, Peoples R China 3.South China Agr Univ, Key Lab Nat Pesticide & Chem Biol, Minist Educ, Guangzhou 510642, Peoples R China 4.Southern Univ Sci & Technol, Guangdong Prov Key Lab Catalysis, Shenzhen 518055, Peoples R China
通讯作者单位	南方科技大学
推荐引用方式 GB/T 7714	Du, Yiming,Chen, Shuxin,Huang, Ao,et al. Diversity-Oriented Synthesis of Fluoromethylated Arenes via Palladium-Catalyzed C-H Fluoromethylation of Aryl Iodides[J]. ORGANIC LETTERS,2022,24(6).
APA	Du, Yiming.,Chen, Shuxin.,Huang, Ao.,Chen, Yihan.,Liu, Yun-Lin.,...&Li, Zhaodong.(2022).Diversity-Oriented Synthesis of Fluoromethylated Arenes via Palladium-Catalyzed C-H Fluoromethylation of Aryl Iodides.ORGANIC LETTERS,24(6).
MLA	Du, Yiming,et al."Diversity-Oriented Synthesis of Fluoromethylated Arenes via Palladium-Catalyzed C-H Fluoromethylation of Aryl Iodides".ORGANIC LETTERS 24.6(2022).