题名 | Efficient genome editing of genes involved in neural crest development using the CRISPR/Cas9 system in Xenopus embryos |
作者 | |
通讯作者 | Chen, Yonglong; Zhao, Hui |
发表日期 | 2016-03-31
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DOI | |
发表期刊 | |
ISSN | 2045-3701
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卷号 | 6 |
摘要 | Background: The RNA guided CRISPR/Cas9 nucleases have been proven to be effective for gene disruption in various animal models including Xenopus tropicalis. The neural crest (NC) is a transient cell population during embryonic development and contributes to a large variety of tissues. Currently, loss-of-function studies on NC development in X. tropicalis are largely based on morpholino antisense oligonucleotide. It is worthwhile establishing targeted gene knockout X. tropicails line using CRISPR/Cas9 system to study NC development. |
关键词 | |
相关链接 | [来源记录] |
收录类别 | |
语种 | 英语
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学校署名 | 通讯
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资助项目 | Shenzhen Key Laboratory of Cell Microenvironment[ZDSYS20140509142721429]
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WOS研究方向 | Biochemistry & Molecular Biology
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WOS类目 | Biochemistry & Molecular Biology
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WOS记录号 | WOS:000373193000001
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出版者 | |
来源库 | Web of Science
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引用统计 |
被引频次[WOS]:13
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成果类型 | 期刊论文 |
条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/29695 |
专题 | 生命科学学院_生物系 南方科技大学医学院 |
作者单位 | 1.Chinese Univ Hong Kong, Sch Biomed Sci, Key Lab Regenerat Med, Minist Educ,Fac Med, Hong Kong, Hong Kong, Peoples R China 2.South Univ Sci & Technol China, Shenzhen Key Lab Cell Microenvironm, Dept Biol, Shenzhen 518055, Guangdong, Peoples R China 3.NCI, Adv Biomed Comp Ctr, NIH, Frederick, MD 21702 USA 4.Ji Nan Univ, Key Lab Regenerat Med, Minist Educ, Guangzhou 510632, Guangdong, Peoples R China 5.KIZ CUHK Joint Lab Bioresources & Mol Res Common, Hong Kong, Hong Kong, Peoples R China 6.Ji Nan Univ, Coll Life Sci & Technol, Dept Dev & Regenerat Biol, Guangzhou 510632, Guangdong, Peoples R China |
通讯作者单位 | 生物系; 南方科技大学医学院 |
推荐引用方式 GB/T 7714 |
Liu, Zhongzhen,Cheng, Tina Tsz Kwan,Shi, Zhaoying,et al. Efficient genome editing of genes involved in neural crest development using the CRISPR/Cas9 system in Xenopus embryos[J]. Cell and Bioscience,2016,6.
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APA |
Liu, Zhongzhen.,Cheng, Tina Tsz Kwan.,Shi, Zhaoying.,Liu, Ziran.,Lei, Yong.,...&Zhao, Hui.(2016).Efficient genome editing of genes involved in neural crest development using the CRISPR/Cas9 system in Xenopus embryos.Cell and Bioscience,6.
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MLA |
Liu, Zhongzhen,et al."Efficient genome editing of genes involved in neural crest development using the CRISPR/Cas9 system in Xenopus embryos".Cell and Bioscience 6(2016).
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