Platinum-Catalyzed Tandem Cyclization Reaction to Multiply Substituted Indolines under Microwave-Assisted Conditions

A convenient platinum-catalyzed tandem cyclization reaction from readily available aminoalkynes and enones has been developed to efficiently prepare multiply substituted indolines in good yields under microwave irradiation within a short reaction time. This efficient reaction is presumed to proceed via a tandem process involving intramolecular hydroamination of aminoalkynes, Michael addition of enones, aldol condensation and intermolecular transfer hydrogenation.