Electronic Transport in Molecular Wires of Precisely Controlled Length Built from Modular Proteins

Zhang, Bintian1,2; Ryan, Eathen3; Wang, Xu3; Song, Weisi1; Lindsay, Stuart4,5

2022

10.1021/acsnano.1c10830

ACS Nano   影响因子和分区

1936-0851

1936-086X

DNA molecular wires have been studied extensively because of the ease with which molecules of controlled length and composition can be synthesized. The same has not been true for proteins. Here, we have synthesized and studied a series of consensus tetratricopeptide repeat (CTPR) proteins, spanning 4 to 20 nm in length, in increments of 4 nm. For lengths in excess of 6 nm, their conductance exceeds that of the canonical molecular wire, oligo(phenylene-ethylenene), because of the more gradual decay of conductance with length in the protein. We show that, while the conductance decay fits an exponential (characteristic of quantum tunneling) and not a linear increase of resistance with length (characteristic of hopping transport), it is also accounted for by a square-law dependence on length (characteristic of weakly driven hopping). Measurements of the energy dependence of the decay length rule out the quantum tunneling case. A resonance in the carrier injection energy shows that allowed states in the protein align with the Fermi energy of the electrodes. Both the energy of these states and the long-range of hopping suggest that the reorganization induced by hole formation is greatly reduced inside the protein. We outline a model for calculating the molecular-electronic properties of proteins.

molecular electronics bioelectronics protein electronics hopping transport tunneling transport molecular wires protein wires

SCI ; EI

英语

NI期刊

其他

National Human Genome Research Institute[1R01HG011079] ; U.S. Army[W911NF2010320]

Chemistry ; Science & Technology - Other Topics ; Materials Science

Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary

WOS:000768174900001

AMER CHEMICAL SOC

20220411537756

Biosynthesis ; Electronic properties ; Molecular electronics ; Nanowires ; Proteins ; Quantum chemistry

Biotechnology:461.8 ; Metal Forming:535.2 ; Nanotechnology:761 ; Biochemistry:801.2 ; Physical Chemistry:801.4 ; Chemical Reactions:802.2 ; Organic Compounds:804.1 ; Atomic and Molecular Physics:931.3 ; Solid State Physics:933

Web of Science

1.Arizona State Univ, Biodesign Inst, Tempe, AZ 85281 USA
2.Southern Univ Sci & Technol, Sch Environm Sci & Engn, Shenzhen 518055, Guangdong, Peoples R China
3.Arizona State Univ, Sch Mol Sci, Tempe, AZ 85281 USA
4.Arizona State Univ, Biodesign Inst, Sch Mol Sci, Tempe, AZ 85281 USA
5.Arizona State Univ, Dept Phys, Tempe, AZ 85281 USA

Zhang, Bintian,Ryan, Eathen,Wang, Xu,et al. Electronic Transport in Molecular Wires of Precisely Controlled Length Built from Modular Proteins[J]. ACS Nano,2022,16(1):1671-1680.

Zhang, Bintian,Ryan, Eathen,Wang, Xu,Song, Weisi,&Lindsay, Stuart.(2022).Electronic Transport in Molecular Wires of Precisely Controlled Length Built from Modular Proteins.ACS Nano,16(1),1671-1680.

Zhang, Bintian,et al."Electronic Transport in Molecular Wires of Precisely Controlled Length Built from Modular Proteins".ACS Nano 16.1(2022):1671-1680.