Long-term exposure to fine particulate matter modifies the association between physical activity and hypertension incidence

Liu，Qiong1,2; Huang，Keyong1; Liang，Fengchao1,3; Yang，Xueli4; Li，Jianxin1; Chen，Jichun1; Liu，Xiaoqing5; Cao，Jie1; Shen，Chong6; Yu，Ling7; Zhao，Yingxin8; Deng，Ying9; Li，Ying1; Hu，Dongsheng10,11; Lu，Xiangfeng1; Liu，Yang12; Gu，Dongfeng1,2,13; Liu，Fangchao1; Huang，Jianfeng1

2022

10.1016/j.jshs.2022.01.004

Journal of Sport and Health Science   影响因子和分区

2095-2546

2213-2961

Background: The trade-off between the benefits of regular physical activity (PA) and the potentially detrimental effects of augmented exposure to air pollution in highly polluted regions remains unclear. This study aimed to examine whether ambient fine particulate matter (PM) exposure modified the impacts of PA volume and intensity on hypertension risk. Methods: We included 54,797 participants without hypertension at baseline in a nationwide cohort of the Prediction for Atherosclerotic Cardiovascular Disease Risk in China (China-PAR) project. PA volume and intensity were assessed by questionnaire, and high-resolution (1×1 km) PM estimates were generated using a satellite-based model. Results: During 413,516 person-years of follow-up, 12,100 incident hypertension cases were identified. PM significantly modified the relationship between PA and hypertension incidence (p < 0.001). Increased PA volume was negatively associated with incident hypertension in the low PM stratum (<59.8 μg/m, p < 0.001), with a hazard ratio (95% confidence interval (95%CI)) of 0.81 (0.74–0.88) when comparing the fourth with the first quartile of PA volume. However, the health benefits were not observed in the high PM stratum (≥59.8 μg/m, p = 0.370). Moreover, compared with light PA intensity, vigorous intensity was related to a 20% (95%CI: 9%–29%) decreased risk of hypertension for participants exposed to low PM, but a 17% (95%CI: 4%–33%) increased risk for those with high PM levels. Conclusion: PA was associated with a reduced risk of hypertension only among participants with low PM exposure. Our findings recommended regular PA to prevent hypertension in less polluted regions and reinforced the importance of air quality improvement.

Air pollution Cohort study Hypertension Particulate matter Physical activity

英语

其他

2-s2.0-85126623136

Scopus

1.Department of Epidemiology,National Center for Cardiovascular Diseases,Fuwai Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,100037,China
2.Key Laboratory of Cardiovascular Epidemiology,Chinese Academy of Medical Sciences,Beijing,100037,China
3.School of Public Health and Emergency Management,Southern University of Science and Technology,Shenzhen,518055,China
4.Tianjin Key Laboratory of Environment,Nutrition and Public Health; Department of Occupational and Environmental Health,School of Public Health,Tianjin Medical University,Tianjin,300070,China
5.Division of Epidemiology,Guangdong Provincial People's Hospital and Cardiovascular Institute,Guangzhou,510080,China
6.Department of Epidemiology and Biostatistics,School of Public Health,Nanjing Medical University,Nanjing,211166,China
7.Department of Cardiology,Fujian Provincial Hospital,Fuzhou,350014,China
8.Cardio-Cerebrovascular Control and Research Center,Institute of Basic Medicine,Shandong First Medical University (Shandong Academy of Medical Sciences),Jinan,250062,China
9.Center for Chronic and Noncommunicable Disease Control and Prevention,Sichuan Center for Disease Control and Prevention,Chengdu,610041,China
10.Department of Epidemiology and Health Statistics,College of Public Health,Zhengzhou University,Zhengzhou,450001,China
11.Department of Biostatistics and Epidemiology,School of Public Health,Shenzhen University Health Science Center,Shenzhen,518071,China
12.Gangarosa Department of Environmental Health,Rollins School of Public Health,Emory University,Atlanta,30322,United States
13.School of Medicine,Southern University of Science and Technology,Shenzhen,518055,China

Liu，Qiong,Huang，Keyong,Liang，Fengchao,et al. Long-term exposure to fine particulate matter modifies the association between physical activity and hypertension incidence[J]. Journal of Sport and Health Science,2022.

Liu，Qiong.,Huang，Keyong.,Liang，Fengchao.,Yang，Xueli.,Li，Jianxin.,...&Huang，Jianfeng.(2022).Long-term exposure to fine particulate matter modifies the association between physical activity and hypertension incidence.Journal of Sport and Health Science.

Liu，Qiong,et al."Long-term exposure to fine particulate matter modifies the association between physical activity and hypertension incidence".Journal of Sport and Health Science (2022).