New insights to atherosclerosis management: Role of nanomaterials

Li，Zhongzhong1; Jiang，Cheng2; Chai，Luxiao3; Fan，Taojian4; Li，Chaozhou3; Chen，Zhi3; Huang，Weichun5; Zhang，Bin3; Al-Hartomy，Omar A.6; Al-Ghamdi，Ahmed6; Wageh，Abdullah Swelm6; Al-Sehemi，G.7; Kang，Lin8,9; Liu，Quan10,11; Liu，Xiaoyun1; Geng，Qingshan2; Xie，Zhongjian12,13; Zhang，Han3

2022-06-01

10.1016/j.apmt.2022.101466

Applied Materials Today   影响因子和分区

2352-9407

2352-9407

Atherosclerosis is a sort of chronic inflammatory disease mainly caused by the accumulation of lipoproteins on the blood vessel walls. Many cardiovascular diseases with high mortality, like ischemic cerebral stroke and ischemic heart disease, are promoted by atherosclerosis. Currently, there is much space for improvement in clinical monitoring and treatment of atherosclerosis. The development of nanotechnology and nanomaterials provides solutions to certain shortcomings of current programs. The present article first reviews the nanomaterials-based therapeutic strategies as well as the related pathogenesis and influencing factors of atherosclerosis. In addition, the main recent developed nanomaterials-based protocols in order to early diagnosis and better monitor for atherosclerosis have been classified and summarized. Subsequently, we list the clinical progress of nanomaterials in the treatment and diagnosis of atherosclerosis in recent years and analyze the current main dilemmas, as well. This review aims to reveal the essential role of nanomaterials in atherosclerosis management and thus provide new insights to promote the further development of nanomaterials-based medicines thus better service in the field of human life and health.

Atherosclerosis Monitor Nanomaterials Pathogenesis Therapy

SCI ; EI

英语

其他

Basic and Applied Basic Research Foundation of Guangdong Province[2019B1515120043];Natural Science Foundation of Guangdong Province[2020A151501612];Guangdong Provincial People's Hospital[DFJH201811];Guangdong Provincial People's Hospital[DFJH201922];Guangdong Provincial People's Hospital[DFJH2020003];

Materials Science

Materials Science, Multidisciplinary

WOS:000804754900002

ELSEVIER

20221511946406

Blood vessels ; Cardiology ; Diagnosis ; Nanostructured materials

Biological Materials and Tissue Engineering:461.2 ; Medicine and Pharmacology:461.6 ; Nanotechnology:761 ; Crystalline Solids:933.1

2-s2.0-85127685139

Scopus

1.Department of Neurology,The Second Hospital of Hebei Medical University,Neurological Laboratory of Hebei Province,Neuroscience Research Center,Medicine and Health Institute,Hebei Medical University,Shijiazhuang,Hebei,050000,China
2.Department of Cardiology,Guangdong Cardiovascular Institute,Guangdong Academy of Medical Sciences,Guangdong Provincial People’ Hospital,Guangzhou,Guangdong,510080,China
3.International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education,Institute of Microscale Optoelectronics,Shenzhen Institute of Translational Medicine,Department of Otolaryngology,Shenzhen Second People's Hospital,The First Affiliated Hospital,Shenzhen University,Shenzhen,518060,China
4.International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education,Institute of Microscale Optoelectronics,College of Health Science and Environmental Engineering,Shenzhen Technology University,Shenzhen,518118,China
5.Nantong Key Lab of Intelligent and New Energy Materials,College of Chemistry and Chemical Engineering,Nantong University,Nantong,Jiangsu,226019,China
6.Department of Physics,Faculty of Science,King Abdulaziz University,Jeddah,21589,Saudi Arabia
7.Department of Chemistry,Faculty of Science,Research Center for Advanced Materials Science (RCAMS),King Khalid University,Abha,P.O. Box 9004,61413,Saudi Arabia
8.Department of Geriatrics,The Second Clinical Medical College,The First Affiliated Hospital,Southern University of Science and Technology,Shenzhen People's Hospital,Jinan University,Shenzhen,Guangdong,518020,China
9.The Biobank of National Innovation Center for Advanced Medical Devices,Shenzhen People's Hospital,Shenzhen,Guangdong,518020,China
10.Department of Hepatobiliary and Pancreas Surgery,The Second Clinical Medical College,Shenzhen people's Hospital,Jinan University,Shenzhen,518020,China
11.Integrated Chinese and Western Medicine Postdoctoral Research Station,Jinan university,Guangzhou,Guangdong,510632,China
12.Institute of Pediatrics,Shenzhen Children's Hospital,Shenzhen,Guangdong,518038,China
13.Shenzhen International Institute for Biomedical Research,Shenzhen,Guangdong,518116,China

Li，Zhongzhong,Jiang，Cheng,Chai，Luxiao,et al. New insights to atherosclerosis management: Role of nanomaterials[J]. Applied Materials Today,2022,27.

Li，Zhongzhong.,Jiang，Cheng.,Chai，Luxiao.,Fan，Taojian.,Li，Chaozhou.,...&Zhang，Han.(2022).New insights to atherosclerosis management: Role of nanomaterials.Applied Materials Today,27.

Li，Zhongzhong,et al."New insights to atherosclerosis management: Role of nanomaterials".Applied Materials Today 27(2022).