南方科技大学知识苑(SUSTech KC): Construction and transformations of 2,2-difluoro-2,3-dihydrofurans from enaminones and diflurocarbene

题名	Construction and transformations of 2,2-difluoro-2,3-dihydrofurans from enaminones and diflurocarbene
作者	Sheng, Heyun 1; Chen, Zhiwei 1; Li, Xue 1; Su, Jianke 1; Song, Qiuling 1,2,3
通讯作者	Song, Qiuling
发表日期	2022-04-01
DOI	10.1039/d2qo00468b
发表期刊	Organic Chemistry Frontiers 影响因子和分区
ISSN	2052-4129
摘要	A simple and efficient construction of 2-difluoro-2,3-dihydrofurans is reported, which features metal-free and additive-free conditions, high functional group tolerance and readily accessible starting materials. It is worth mentioning that this type of compound could be readily converted into alpha-amino acids under a reducing atmosphere; moreover, the synthesis of 2-fluorofurans could also be completed through the fluorine elimination in the presence of magnesium powder and TBSCl. This method will open up new avenues for the research and development of amino acid drugs and it is also a novel and undeveloped strategy for the construction of 2-fluorofuran derivatives.
相关链接	[来源记录]
收录类别	SCI ; EI
语种	英语
学校署名	通讯
资助项目	National Natural Science Foundation[21931013] ; Guangdong Provincial Key Laboratory of Catalysis[2020B121201002]
WOS研究方向	Chemistry
WOS类目	Chemistry, Organic
WOS记录号	WOS:000787852400001
出版者	ROYAL SOC CHEMISTRY
EI入藏号	20222012106875
EI分类号	Organic Compounds:804.1
来源库	Web of Science
引用统计	被引频次[WOS]：24
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/333762
专题	南方科技大学
作者单位	1.Huaqiao Univ, Inst Next Generat Matter Transformat, Coll Mat Sci Engn, 668 Jimei Blvd, Xiamen 361021, Fujian, Peoples R China 2.Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Henan, Peoples R China 3.Southern Univ Sci & Technol, Guangdong Prov Key Lab Catalysis, Shenzhen 518055, Guangdong, Peoples R China
通讯作者单位	南方科技大学
推荐引用方式 GB/T 7714	Sheng, Heyun,Chen, Zhiwei,Li, Xue,et al. Construction and transformations of 2,2-difluoro-2,3-dihydrofurans from enaminones and diflurocarbene[J]. Organic Chemistry Frontiers,2022.
APA	Sheng, Heyun,Chen, Zhiwei,Li, Xue,Su, Jianke,&Song, Qiuling.(2022).Construction and transformations of 2,2-difluoro-2,3-dihydrofurans from enaminones and diflurocarbene.Organic Chemistry Frontiers.
MLA	Sheng, Heyun,et al."Construction and transformations of 2,2-difluoro-2,3-dihydrofurans from enaminones and diflurocarbene".Organic Chemistry Frontiers (2022).