Application Value of Color Doppler Ultrasonography Combined with Thyroid Autoantibody Tests in Early Diagnosis of Thyroid Cancer

Song，Danlin1; Dong，Fajin1; Zheng，Jing1; Luo，Hui1; Wei，Jinxi2

2022

10.1155/2022/5248230

Computational and Mathematical Methods in Medicine   影响因子和分区

1748-670X

1748-6718

Objective. To explore the application value of color Doppler ultrasonography combined with thyroid autoantibody tests in the early diagnosis of thyroid cancer. Methods. The medical data of 100 patients with thyroid nodules treated in our hospital from June 2019 to June 2021 were retrospectively analyzed; all patients received color Doppler ultrasonography and thyroid autoantibody tests before surgery and were divided into the benign lesion group (n=45) and the malignant lesion group (n=55) according to the postoperative pathological findings (the gold standard), so as to compare and analyze the application value of color Doppler ultrasonography, thyroid autoantibody tests, and their combination in the early diagnosis of thyroid cancer. Results. Compared with the pathological findings, the accuracy rate, sensitivity, specificity, positive predictive value, and negative predictive value of the combined diagnosis were significantly higher than those in the single diagnosis of color Doppler ultrasonography, TgAb test, TPOAb test, and TRAb test (P<0.05), and by plotting the ROC curves to analyze the effect of these modalities in diagnosing early thyroid diseases, the results showed that the areas under the curve from large to small were combined diagnosis, color Doppler ultrasonography, TgAb test, TPOAb test, and TRAb test. Conclusion. Color Doppler ultrasonography has many advantages in the diagnosis of thyroid nodules, such as easy operation, painlessness, noninvasiveness, high efficiency, and repeatable detection, and the high-definition probe is able to show tiny lesions, echogenicity, blood flow signal, and other characteristics of foci. Combining color Doppler ultrasonography with testing thyroid autoantibodies such as TgAb, TPOAb, and TRAb can effectively improve the detection rate of early thyroid cancer, presenting significant reference value and meaning to clinical diagnosis and treatment of thyroid cancer.

SCI ; EI

英语

第一 ; 通讯

Mathematical & Computational Biology

Mathematical & Computational Biology

WOS:000796770400005

HINDAWI LTD

2-s2.0-85129986129

Scopus

1.Department of Ultrasound,Shenzhen People's Hospital,2nd Clinical Medical College of Jinan University,1st Affiliated Hospital of Southern University of Science and Technology,Shenzhen,Guangdong,518020,China
2.Department of Radiology,Shenzhen People's Hospital,2nd Clinical Medical College of Jinan University,1st Affiliated Hospital of Southern University of Science and Technology,Shenzhen,Guangdong,518020,China

Song，Danlin,Dong，Fajin,Zheng，Jing,et al. Application Value of Color Doppler Ultrasonography Combined with Thyroid Autoantibody Tests in Early Diagnosis of Thyroid Cancer[J]. Computational and Mathematical Methods in Medicine,2022,2022.

Song，Danlin,Dong，Fajin,Zheng，Jing,Luo，Hui,&Wei，Jinxi.(2022).Application Value of Color Doppler Ultrasonography Combined with Thyroid Autoantibody Tests in Early Diagnosis of Thyroid Cancer.Computational and Mathematical Methods in Medicine,2022.

Song，Danlin,et al."Application Value of Color Doppler Ultrasonography Combined with Thyroid Autoantibody Tests in Early Diagnosis of Thyroid Cancer".Computational and Mathematical Methods in Medicine 2022(2022).