南方科技大学知识苑(SUSTech KC): Structural basis for histone H3 recognition by NASP in Arabidopsis

题名	Structural basis for histone H3 recognition by NASP in Arabidopsis
作者	Liu，Yanhong1,2 ; Chen，Liu1 ; Wang，Na1 ; Wu，Baixing 1; Bao，Hongyu1 ; Huang，Hongda1
通讯作者	Bao，Hongyu; Huang，Hongda
发表日期	2022
DOI	10.1111/jipb.13277
发表期刊	Journal of Integrative Plant Biology 影响因子和分区
ISSN	1672-9072
EISSN	1744-7909
摘要	The structural basis for histone recognition by the histone chaperone nuclear autoantigenic sperm protein (NASP) remains largely unclear. Here, we showed that Arabidopsis thaliana AtNASP is a monomer and displays robust nucleosome assembly activity in vitro. Examining the structure of AtNASP complexed with a histone H3 α3 peptide revealed a binding mode that is conserved in human NASP. AtNASP recognizes the H3 N-terminal region distinct from human NASP. Moreover, AtNASP forms a co-chaperone complex with ANTI-SILENCING FUNCTION 1 (ASF1) by binding to the H3 N-terminal region. Therefore, we deciphered the structure of AtNASP and the basis of the AtNASP–H3 interaction.
关键词	Arabidopsis NASP ASF1 crystal structure epigenetics histone chaperone histone H3
相关链接	[Scopus记录]
收录类别	SCI
语种	英语
学校署名	第一 ; 通讯
资助项目	National Key R&D Program of China[2018YFC1004500] ; Natural Science Foundation of Guangdong Province[2022A1515010501] ; Chinese National Natural Science Foundation[32171206,31800619] ; Shenzhen Science and Technology Program[KQTD20190929173906742] ; Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes[2019KSYS006] ; Shenzhen Government 'Peacock Plan'[Y01226136]
WOS研究方向	Biochemistry & Molecular Biology ; Plant Sciences
WOS类目	Biochemistry & Molecular Biology ; Plant Sciences
WOS记录号	WOS:000810046300001
出版者	WILEY
Scopus记录号	2-s2.0-85131721211
来源库	Scopus
引用统计	被引频次[WOS]：3
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/336287
专题	生命科学学院_生物系生命科学学院
作者单位	1.Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes,Department of Biology,School of Life Sciences,Southern University of Science and Technology,Shenzhen,518055,China 2.School of Life Science and Technology,Harbin Institute of Technology,Harbin,150080,China
第一作者单位	生物系; 生命科学学院
通讯作者单位	生物系; 生命科学学院
第一作者的第一单位	生物系; 生命科学学院
推荐引用方式 GB/T 7714	Liu，Yanhong,Chen，Liu,Wang，Na,et al. Structural basis for histone H3 recognition by NASP in Arabidopsis[J]. Journal of Integrative Plant Biology,2022.
APA	Liu，Yanhong,Chen，Liu,Wang，Na,Wu，Baixing,Bao，Hongyu,&Huang，Hongda.(2022).Structural basis for histone H3 recognition by NASP in Arabidopsis.Journal of Integrative Plant Biology.
MLA	Liu，Yanhong,et al."Structural basis for histone H3 recognition by NASP in Arabidopsis".Journal of Integrative Plant Biology (2022).