超声弹性成像对伴后方回声衰减乳腺结节的鉴别诊断价值

目的:探索超声弹性成像对伴后方回声衰减的乳腺结节的鉴别诊断价值。方法:选取2017年6月至2019年10月深圳市人民医院105例伴后方回声衰减的乳腺结节患者，常规超声检查后运用超宽波束追踪技术进入超声弹性成像模式，获得弹性模量最大值(Emax)、平均值(Emean)、最小值(Emin以及脂肪组织一结节和应变比(B/A)，行手术或粗针穿刺活检得到病理结果。以病理结果为诊断金标准，比较超声弹性参数在伴后方回声衰减的乳腺良恶性结节之间的差异，并采用ROC曲线对Emax进行分析。结果:105例中良性结节65例，恶性结节40例。Emax、Emean和B/A在有声衰减的良恶性乳腺结节间差异有统计学意义( P<0.05)。以Emax 95 kPa为截点，ROC曲线下面积为0.817，诊断乳腺良恶性肿块的敏感性为88%，特异性为72%。 结论:超声弹性成像对鉴别诊断有声衰减的乳腺结节良恶性有很高价值，对治疗方案的制定有一定意义。;Objective:To explore the differential diagnostic value of ultrasonic elastography for breast nodules with acoustic attenuation.Methods:A total of 105 cases with breast nodules with posterior echo attenuation from June 2017 to October 2019 in Shenzhen People′s Hospital were enrolled. Routine ultrasound examination and elastography were performed and maximum of elastography(Emax), mean of elastography value(Emean), minimum of elastography value(Emin) and strain ratio of fat/strain ratio of nodules(B/A) were recorded. With the pathological results as the diagnosed gold standard, elastic parameters different between benign and malignant breast nodules with posterior echo attenuation were compared. And the Emax value of elastic imaging was analyzed by the ROC curve.Results:There were 65 cases of benign nodules and 40 cases of malignancy. The difference of ultrasound E imaging were statistically significant for judging benign and malignant breast nodules with acoustic attenuation( P<0.05). When Emax 95 kPa was set as the cut-off value for the differential diagnosis of benign and malignat breast nodules, the area under the ROC curve was 0.817, and the sensitivity was 88% and the specificity was 72%. Conclusions:Ultrasonic elastrography is of great value for differential diagnosis of benign and malignant breast nodules with acoustic attenuation, and it is important for the decision making of clinical treatment plan.