Breathable and Stretchable Dressings for Accelerating Healing of Infected Wounds

Wang, Le1; Zheng, Wenfu2; Hou, Qinghong1; Zhong, Leni1; Li, Qizhen1; Jiang, Xingyu1

2022-07-01

10.1002/adhm.202201053

Advanced Healthcare Materials   影响因子和分区

2192-2640

2192-2659

Multidrug-resistant (MDR) bacteria-infected wounds are challenging issues that threaten human health. Herein, L-thioproline (T) and Boc-capped L-thioproline (BT)-decorated gold nanoparticles (TBT-GNPs) with potent antibacterial activity against MDR bacteria are reported. The TBT-GNPs are composited with bacterial cellulose to form wound dressings which show excellent antimicrobial performance both in vitro and in vivo. Moreover, this dressing is both breathable and stretchable which is favorable for gas exchange to accelerate the wound healing. This work is insightful for developing multifunctional dressings to satisfy the clinical requirements.

antibacterial activity gold nanoparticles L-thioproline multidrug-resistant bacteria wound dressing

SCI ; EI

英语

第一 ; 通讯

National Key R&D Program of China[2018YFA0902600] ; National Natural Science Foundation of China["81730051","32071390"] ; Shenzhen Science and Technology Program[KQTD20190929172743294] ; Guangdong Provincial Key Laboratory of Advanced Biomaterials[2022B1212010003] ; Shenzhen Key Laboratory of Smart Healthcare Engineering[ZDSYS20200811144003009] ; Guangdong Innovative and Entrepreneurial Research Team Program[2019ZT08Y191]

Engineering ; Science & Technology - Other Topics ; Materials Science

Engineering, Biomedical ; Nanoscience & Nanotechnology ; Materials Science, Biomaterials

WOS:000822546200001

WILEY

20222812341475

Bacteria ; Fiber optic sensors ; Metal nanoparticles

Fiber Optics:741.1.2 ; Nanotechnology:761

Web of Science

1.Southern Univ Sci & Technol, Dept Biomed Engn, Guangdong Prov Key Lab Adv Biomat, Shenzhen Key Lab Smart Healthcare Engn, 1088 Xueyuan Rd, Shenzhen 518055, Guangdong, Peoples R China
2.Natl Ctr NanoSci & Technol, GBA Res Innovat Inst Nanotechnol, CAS Key Lab Biol Effects Nanomat & Nanosafety, 11 Zhongguancun Beiyitiao, Beijing 100190, Peoples R China

Wang, Le,Zheng, Wenfu,Hou, Qinghong,et al. Breathable and Stretchable Dressings for Accelerating Healing of Infected Wounds[J]. Advanced Healthcare Materials,2022,11.

Wang, Le,Zheng, Wenfu,Hou, Qinghong,Zhong, Leni,Li, Qizhen,&Jiang, Xingyu.(2022).Breathable and Stretchable Dressings for Accelerating Healing of Infected Wounds.Advanced Healthcare Materials,11.

Wang, Le,et al."Breathable and Stretchable Dressings for Accelerating Healing of Infected Wounds".Advanced Healthcare Materials 11(2022).