Analysis of the Physiological Roles and Mode of Actions of Phthalimides as GA Signal Regulator in Rice

Jiang, Kai1; Wang, Jianwen2; Ito, Shinsaku3; Takahashi, Ikuo2; Ohta, Tsuyoshi2; Murase, Kohji2; Nakajima, Masatoshi2; Guo, Hongwei1; Takayama, Seiji2; Asami, Tadao2

2022-08-01

10.1007/s00344-022-10733-y

JOURNAL OF PLANT GROWTH REGULATION   影响因子和分区

0721-7595

1435-8107

An N-substituted phthalimide, AC94377, was reported to mimic gibberellin (GA) activity in various plants, and was demonstrated to be a selective agonist for GA receptor GID1 in Arabidopsis, suggesting its potentiality for developing novel GA signal regulators. Here, we confirmed the GA-like activity of AC94377 in rice, including promotion on 2nd leaf sheath growth and suppression on strigolactone exudates from roots. We performed chemical and genetic manipulation of interaction between rice GA receptor GID1 and phthalimides. Our results showed that modifications of carboxamide moiety of AC94377 can interchange the preference for different GID1-subtype. To summary, our findings confirmed universal roles of AC94377 as a GID1 agonist, and the potentiality of designing novel GA agonist or even antagonist based on the scaffold of AC94377 coupled with GID1 manipulations in crops, which could be used for root parasitic weed control.

Gibberellin GID1 Agonist AC94377 Structure-activity study

SCI

英语

第一

National Natural Science Foundation of China["21907049","31911540070"] ; Japan International Cooperation Agency, Science and Technology Research Partnership for Sustainable Development, Japan Society for the Promotion of Science, Guangdong Province Introduction of Innovative RD Team[2016ZT06S172] ; Shenzhen Science and Technology Program[KYTDPT20181011104005] ; China Scholarship Council[201908050180]

Plant Sciences

Plant Sciences

WOS:000837920500002

SPRINGER

PLANT & ANIMAL SCIENCE

Web of Science

1.Southern Univ Sci & Technol SUSTech, Sch Life Sci, Inst Plant & Food Sci, Dept Biol, Shenzhen 518055, Guangdong, Peoples R China
2.Univ Tokyo, Grad Sch Agr & Life Sci, Tokyo, Japan
3.Tokyo Univ Agr, Dept Biosci, Tokyo, Japan

Jiang, Kai,Wang, Jianwen,Ito, Shinsaku,et al. Analysis of the Physiological Roles and Mode of Actions of Phthalimides as GA Signal Regulator in Rice[J]. JOURNAL OF PLANT GROWTH REGULATION,2022,42(4).

Jiang, Kai.,Wang, Jianwen.,Ito, Shinsaku.,Takahashi, Ikuo.,Ohta, Tsuyoshi.,...&Asami, Tadao.(2022).Analysis of the Physiological Roles and Mode of Actions of Phthalimides as GA Signal Regulator in Rice.JOURNAL OF PLANT GROWTH REGULATION,42(4).

Jiang, Kai,et al."Analysis of the Physiological Roles and Mode of Actions of Phthalimides as GA Signal Regulator in Rice".JOURNAL OF PLANT GROWTH REGULATION 42.4(2022).