The research progress of exhaled volatile organic compounds on the COVID-19 呼出气挥发性有机物在 COVID-19 中的研究进展

Wu，Chao Ling1; Chen，Yuan Rong1; Fu，Liang2; Deng，Guo Fang2; Yuan，Xiao Liang3

2022-07-01

10.13604/j.cnki.46-1064/r.2022.07.18

中国热带医学   影响因子和分区

1009-9727

Coronavirus disease 2019 (COVID-19) is a highly contagious respiratory disease that can be transmitted through human exhaled breath and has a huge impact on global public health. Early diagnosis of COVID-19 and isolation of positive cases have proven to be fundamental to containing the spread of infection. While polymerase chain reaction (PCR)based methods remain the gold standard for diagnosing COVID-19, the urgent need for rapid and large-scale diagnosis has promote to the development of alternative diagnosis methods. Volatile organic compounds (VOCs) have shown great potential as biomarkers for a variety of diseases. VOC profiles can be altered by the pathogen itself, host-pathogen interactions, or host immune responses during infection. Exhaled VOC-based detection technology provides a simple, rapid, non-invasive, and immediate diagnostic method that is expected to be a promising alternative for large-scale screening and ultimately optimizing COVID-19 prevention and control strategies. In here, we have reviewed the principle of VOC detection for COVID-19, the current research status, the existing shortcomings and the prospects.

biomarkers Corona virus disease 2019 exhaled breath volatile organic compounds

中文

其他

2-s2.0-85135771747

Scopus

1.First Clinical Medical College of Gannan Medical University,Ganzhou,Jiangxi,341000,China
2.Second Department of Pulmonary Diseases,Third People's Hospital of Shenzhen Affiliated to South University of Science and Technology,Shenzhen,Guangdong,518112,China
3.Department of Pneumology,First Affiliated Hospital of Gannan Medical University,Ganzhou,Jiangxi,341000,China

Wu，Chao Ling,Chen，Yuan Rong,Fu，Liang,等. The research progress of exhaled volatile organic compounds on the COVID-19 呼出气挥发性有机物在 COVID-19 中的研究进展[J]. 中国热带医学,2022,22(7):685-690.

Wu，Chao Ling,Chen，Yuan Rong,Fu，Liang,Deng，Guo Fang,&Yuan，Xiao Liang.(2022).The research progress of exhaled volatile organic compounds on the COVID-19 呼出气挥发性有机物在 COVID-19 中的研究进展.中国热带医学,22(7),685-690.

Wu，Chao Ling,et al."The research progress of exhaled volatile organic compounds on the COVID-19 呼出气挥发性有机物在 COVID-19 中的研究进展".中国热带医学 22.7(2022):685-690.