| 题名 | Copper-catalyzed radical trans-selective hydroboration of ynamides with N-heterocyclic carbene boranes |
| 作者 | |
| 通讯作者 | Xu，Jing; Wang，Yukun |
| 发表日期 | 2022-09-16
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| DOI | |
| 发表期刊 | |
| EISSN | 2589-0042
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| 卷号 | 25期号:9 |
| 摘要 | Vinylboron compounds are important compounds in organic chemistry and biology. In this communication, we developed a copper(I)-catalyzed, highly regio- and stereoselective radical trans-hydroboration of ynamides with N-heterocyclic carbene (NHC)-ligated borane is reported, which leads to a series of trans-boryl enmides that can be conveniently transformed into various multi-substituted enamides. Further investigation showcased that our method is robust and scalable. The mechanism of this unique reaction is studied and discussed. |
| 关键词 | |
| 相关链接 | [Scopus记录] |
| 收录类别 | |
| 语种 | 英语
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| 学校署名 | 第一
; 通讯
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| 资助项目 | Guangdong Provincial Key Laboratory Of Catalysis[2020B121201002]
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| Scopus记录号 | 2-s2.0-85136576290
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| 来源库 | Scopus
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| 引用统计 |
被引频次[WOS]：0
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| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/395054 |
| 专题 | 南方科技大学医学院_药理学系 南方科技大学医学院 理学院_化学系 深圳格拉布斯研究院 南方科技大学医院 |
| 作者单位 | 1.Department of Pharmacology,School of Medicine,Southern University of Science and Technology,Shenzhen,518055,China 2.Department of Pharmacy,Southern University of Science and Technology Hospital,Shenzhen,518055,China 3.Department of Chemistry and Shenzhen Grubbs Institute and Guangdong Provincial Key Laboratory of Catalysis and Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis,Southern University of Science and Technology,Shenzhen,518055,China 4.Clinical Medical Research Center,Southern University of Science and Technology Hospital,Shenzhen,518055,China |
| 第一作者单位 | 药理学系; 南方科技大学医学院 |
| 通讯作者单位 | 化学系; 深圳格拉布斯研究院; 药理学系; 南方科技大学医学院; 南方科技大学医院 |
| 第一作者的第一单位 | 药理学系; 南方科技大学医学院 |
| 推荐引用方式 GB/T 7714 |
Wang，Kefeng,Yu，Qingzhen,Mao，Wenli,et al. Copper-catalyzed radical trans-selective hydroboration of ynamides with N-heterocyclic carbene boranes[J]. iScience,2022,25(9).
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| APA |
Wang，Kefeng,Yu，Qingzhen,Mao，Wenli,Zheng，Yuxin,Xu，Jing,&Wang，Yukun.(2022).Copper-catalyzed radical trans-selective hydroboration of ynamides with N-heterocyclic carbene boranes.iScience,25(9).
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| MLA |
Wang，Kefeng,et al."Copper-catalyzed radical trans-selective hydroboration of ynamides with N-heterocyclic carbene boranes".iScience 25.9(2022).
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| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | 操作 | |
| Copper-catalyzed rad（2264KB） | -- | -- | 开放获取 | -- | 浏览 | |
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