Enantioselective Silylation of Aliphatic C-H Bonds for the Synthesis of Silicon-Stereogenic Dihydrobenzosiloles

Yang，Bo; Yang，Wu; Guo，Yonghong; You，Lijun; He，Chuan

2020

10.1002/ANGE.202009912

ADVANCED MATERIALS   影响因子和分区

0935-9648

1521-4095

A rhodium(l)-catalyzed enantioselective silylation of aliphatic C-H bonds for the synthesis of silicon-stereogenic dihydrobenzosiloles is demonstrated. This reaction involves a highly enantioselective intramolecular C(sp)-H silylation of dihydrosilanes, followed by a stereospecific intermolecular al- kene hydrosilylation leading to the asymmetrically tetrasub- stituted silanes A wide range of dihydrosilanes and alkenes displaying various functional groups are compatible with this process, giving access to a variety of highly functionalized si- licon-stereogenic dihydrobenzosiloles in good to excellent yields and enantioselectivities.

asymmetric catalysis C(sp3)-H silylation dihydrobenzosiloles hydrosilylation silanes

EI

英语

第一 ; 通讯

20223412618107

Catalysis ; Enantioselectivity ; Silanes ; Silicon

Nonferrous Metals and Alloys excluding Alkali and Alkaline Earth Metals:549.3 ; Physical Chemistry:801.4 ; Chemical Reactions:802.2 ; Organic Compounds:804.1

MATERIALS SCIENCE

2-s2.0-85136188801

Scopus

Shenzhen Grubbs Institute and Department of Chemistry,Guangdong Provincial Key Laboratory of Catalysis,Southern University of Science and Technology,Shenzhen,Guangdong,518055,China

Yang，Bo,Yang，Wu,Guo，Yonghong,et al. Enantioselective Silylation of Aliphatic C-H Bonds for the Synthesis of Silicon-Stereogenic Dihydrobenzosiloles[J]. ADVANCED MATERIALS,2020,132(49):22401-22406.

Yang，Bo,Yang，Wu,Guo，Yonghong,You，Lijun,&He，Chuan.(2020).Enantioselective Silylation of Aliphatic C-H Bonds for the Synthesis of Silicon-Stereogenic Dihydrobenzosiloles.ADVANCED MATERIALS,132(49),22401-22406.

Yang，Bo,et al."Enantioselective Silylation of Aliphatic C-H Bonds for the Synthesis of Silicon-Stereogenic Dihydrobenzosiloles".ADVANCED MATERIALS 132.49(2020):22401-22406.