南方科技大学知识苑(SUSTech KC): A Case of Secondary Pulmonary Syphilis-The Utility of mNGS in Bronchoalveolar Lavage Fluid: A Case Report

题名	A Case of Secondary Pulmonary Syphilis-The Utility of mNGS in Bronchoalveolar Lavage Fluid: A Case Report
作者	Yang, Xue 1,2 ; Wu, Weigang 2,3; Wang, Yongjie 1,2; Wu, Wen 1,2; Huang, Xia 1,2; Xu, Li 4
通讯作者	Xu, Li
发表日期	2022
DOI	10.2147/IDR.S373711
发表期刊	Infection and Drug Resistance 影响因子和分区
ISSN	1178-6973
卷号	15
摘要	Syphilis is a sexually transmitted infectious disease caused by Treponema pallidum. Here, we report a rare case of secondary pulmonary syphilis, which was diagnosed by metagenomic next-generation sequencing (mNGS) in bronchoalveolar lavage fluid (BALF). Direct pulmonary involvement by T. pallidum was suggested by a positive mNGS result in BALF. One month after treatment with benzathine penicillin G (2.4 million units, three doses), a repeated CT scan showed the radiological resolution. To our knowledge, this is the first reported case of secondary pulmonary syphilis diagnosed by mNGS in BALF.
关键词	pulmonary secondary syphilis Treponema pallidum mNGS
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	其他
WOS研究方向	Infectious Diseases ; Pharmacology & Pharmacy
WOS类目	Infectious Diseases ; Pharmacology & Pharmacy
WOS记录号	WOS:000854912900001
出版者	DOVE MEDICAL PRESS LTD
来源库	Web of Science
引用统计	被引频次[WOS]：3
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/402351
专题	南方科技大学第一附属医院
作者单位	1.Jinan Univ, Shenzhen Peoples Hosp, Shenzhen Inst Resp Dis, Clin Med Coll 2, Guangzhou, Peoples R China 2.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen, Guangdong, Peoples R China 3.Jinan Univ, Shenzhen Peoples Hosp The, Dept Infect Dis, Clin Med Coll 2, Guangzhou, Peoples R China 4.First Peoples Hosp Chongqing Liangjiang New Area, Dept Resp & Crit Care Med, Chongqing, Peoples R China
第一作者单位	南方科技大学第一附属医院
推荐引用方式 GB/T 7714	Yang, Xue,Wu, Weigang,Wang, Yongjie,et al. A Case of Secondary Pulmonary Syphilis-The Utility of mNGS in Bronchoalveolar Lavage Fluid: A Case Report[J]. Infection and Drug Resistance,2022,15.
APA	Yang, Xue,Wu, Weigang,Wang, Yongjie,Wu, Wen,Huang, Xia,&Xu, Li.(2022).A Case of Secondary Pulmonary Syphilis-The Utility of mNGS in Bronchoalveolar Lavage Fluid: A Case Report.Infection and Drug Resistance,15.
MLA	Yang, Xue,et al."A Case of Secondary Pulmonary Syphilis-The Utility of mNGS in Bronchoalveolar Lavage Fluid: A Case Report".Infection and Drug Resistance 15(2022).