南方科技大学知识苑(SUSTech KC): Outcomes after lung transplantation among Chinese patients with connective tissue disease-associated interstitial lung disease and pulmonary hypertension: a retrospective cohort study

题名	Outcomes after lung transplantation among Chinese patients with connective tissue disease-associated interstitial lung disease and pulmonary hypertension: a retrospective cohort study
作者	Ju，Chunrong 1; Lian，Qiaoyan 1; Chen，Ao 1; Xu，Xin 1; Zhang，Jianheng 1; Luo，Qun 1; Huang，Danxia 1; Chen，Rongchang 2; He，Jianxing 3
发表日期	2022-09-01
DOI	10.55563/clinexprheumatol/hld9sf
发表期刊	CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 影响因子和分区
ISSN	0392-856X
卷号	40 期号:9页码:1666-1673
摘要	OBJECTIVES: The present study aimed to compare the post-lung transplant survival and complications of connective tissue disease (CTD)-related interstitial lung disease (ILD) and/or pulmonary arterial hypertension with idiopathic pulmonary fibrosis (IPF). METHODS: The clinical data of patients with CTD-ILD or IPF who received lung transplantation between 2015 and 2020 were retrospectively reviewed. Cumulative survival rates after transplantation were estimated using the Kaplan-Meier method. RESULTS: The study included 31 patients with confirmed CTD-ILD and 98 with IPF. Patients with CTD-ILD were significantly younger (53.2 ± 13.7 vs. 62.3 ± 7.2 years, p=0.001) and more likely female (61.3% vs. 7.1%, p<0.001) than patients with IPF. No significant difference was noticed in the 1-year and 5-year survival rates between CTD-ILD and IPF patients (1-year, 73.2% vs 71.4%, p=0.76; 5-year, 69.1% vs. 39.5%, p=0.21). The incidence of primary graft dysfunction was significantly higher in CTD-ILD patients (90.3% vs. 70.4%, p=0.03), while there was no significant difference in primary graft dysfunction-related mortality (6.5% vs. 6.1%, p=0.95) between the two groups. CONCLUSIONS: There was no significant difference in post-lung transplant survival and complications between CTD-ILD and IPF.
相关链接	[Scopus记录]
语种	英语
学校署名	其他
ESI学科分类	CLINICAL MEDICINE
Scopus记录号	2-s2.0-85138457662
来源库	Scopus
引用统计	被引频次[WOS]：0
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/402723
专题	南方科技大学第一附属医院
作者单位	1.First Affiliated Hospital of Guangzhou Medical University,State Key Laboratory of Respiratory Disease,National Clinical Research Center for Respiratory Disease,Guangzhou Institute of Respiratory Health,Guangzhou,China 2.Southern University of Science and Technology,Second Clinical Medical College of Jinan University,Shenzhen People's Hospital,Shenzhen Institute of Respiratory Diseases,Shenzhen,China 3.First Affiliated Hospital of Guangzhou Medical University,State Key Laboratory of Respiratory Disease,National Clinical Research Center for Respiratory Disease,Guangzhou Institute of Respiratory Health,Guangzhou,China
推荐引用方式 GB/T 7714	Ju，Chunrong,Lian，Qiaoyan,Chen，Ao,et al. Outcomes after lung transplantation among Chinese patients with connective tissue disease-associated interstitial lung disease and pulmonary hypertension: a retrospective cohort study[J]. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY,2022,40(9):1666-1673.
APA	Ju，Chunrong.,Lian，Qiaoyan.,Chen，Ao.,Xu，Xin.,Zhang，Jianheng.,...&He，Jianxing.(2022).Outcomes after lung transplantation among Chinese patients with connective tissue disease-associated interstitial lung disease and pulmonary hypertension: a retrospective cohort study.CLINICAL AND EXPERIMENTAL RHEUMATOLOGY,40(9),1666-1673.
MLA	Ju，Chunrong,et al."Outcomes after lung transplantation among Chinese patients with connective tissue disease-associated interstitial lung disease and pulmonary hypertension: a retrospective cohort study".CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 40.9(2022):1666-1673.