One-Step Method for Material Quantitation Using In-Line Tomography With Single Scanning

Suyu Liao1; Shiwo Deng2; Yining Zhu2; Huitao Zhang2; Peiping Zhu3; Kai Zhang3; Xing Zhao2

2022

10.1109/TBME.2022.3181153

IEEE Transactions on Biomedical Engineering   影响因子和分区

1558-2531

1558-2531

Quantitative technique based on In-line phase-contrast computed tomography with single scanning attracts more attention in application due to the flexibility of the implementation. However, the quantitative results usually suffer from artifacts and noise since the phase retrieval and reconstruction are independent ("two-step") without feedback from the original data. The work aims to investigate a method for material quantitation to improve the image quality of In-line tomography within single scanning. Method: An iterative method based Fresnel diffraction imaging model is developed in this work, which directly reconstructs the refractive index decrement delta and imaginary beta of the object from observed data ("one-step"). Moreover, high-quality material decomposition results are obtained by using a linear approximation in the iterative process. Results: Compared with the existing methods, Our method shows a higher peak signal-to-noise ratio and structural similarity in numerical experimental results. Additionally, the quantitation accuracy of the proposed method is greater than 97.2% by calculating the equivalent atomic number of the decomposed basic material in the real experiment. Conclusion: We demonstrate that this one-step method greatly reduces noise and improves quantitative reconstruction and decomposition results. Significance: This algorithm has the potential for quantitative imaging research using In-line tomography in future biomedical applications.

Computed tomography material quantitation linear approximation single scanning phase-contrast one-step method

SCI ; EI

英语

其他

National Natural Science Foundation of China["61971293","61827809","61671311"] ; Sino-German Center[M-0187] ; National Key Research and Development Programof China[2020YFA0712200]

Engineering

Engineering, Biomedical

WOS:000936179400003

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC

20222612276278

Atoms ; Bioinformatics ; Computerized tomography ; Image enhancement ; Image reconstruction ; Latexes ; Medical applications ; Numerical methods ; Refractive index ; Scanning ; Signal to noise ratio

Bioinformatics:461.8.2 ; Information Theory and Signal Processing:716.1 ; Computer Applications:723.5 ; Light/Optics:741.1 ; Colloid Chemistry:801.3 ; Numerical Methods:921.6 ; Atomic and Molecular Physics:931.3

ENGINEERING

IEEE

1.School of Mathematical Sciences, Capital Normal University, Beijing, Haidian District, China
2.Shenzhen National Applied Mathematics Center, Southern University of Science and Technology, Shenzhen, Guangdong Province, China
3.Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, Xicheng District, China

Suyu Liao,Shiwo Deng,Yining Zhu,et al. One-Step Method for Material Quantitation Using In-Line Tomography With Single Scanning[J]. IEEE Transactions on Biomedical Engineering,2022,PP(99):1-12.

Suyu Liao.,Shiwo Deng.,Yining Zhu.,Huitao Zhang.,Peiping Zhu.,...&Xing Zhao.(2022).One-Step Method for Material Quantitation Using In-Line Tomography With Single Scanning.IEEE Transactions on Biomedical Engineering,PP(99),1-12.

Suyu Liao,et al."One-Step Method for Material Quantitation Using In-Line Tomography With Single Scanning".IEEE Transactions on Biomedical Engineering PP.99(2022):1-12.