Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice

Zhou, Tian1; Li, Yuxin2,3; Li, Xiaoyu2,3; Zeng, Fanzhuo2,4; Rao, Yanxia5,6; He, Yang2,3; Wang, Yafei2,3; Liu, Meizhen7; Li, Dali7; Xu, Zhen1; Zhou, Xin2; Du, Siling2,6; Niu, Fugui8; Peng, Jiyun9; Mei, Xifan4; Ji, Sheng-Jian8; Shu, Yousheng2,3; Lu, Wei2,3; Guo, Feifan2; Wu, Tianzhun1; Yuan, Ti Fei6; Mao, Ying3; Peng, Bo2,3,10

2022-10-24

10.1038/s41467-022-33932-3

Nature Communications   影响因子和分区

2041-1723

SCI

英语

NI论文

其他

National Outstanding Youth Science Fund Project of National Natural Science Foundation of China[32170958]

Science & Technology - Other Topics

Multidisciplinary Sciences

WOS:000871563700004

NATURE PORTFOLIO

2-s2.0-85140563371

Scopus

1.Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen,Guangdong,518055,China
2.Department of Neurology,Jinshan Hospital,Institute for Translational Brain Research,State Key Laboratory of Medical Neurobiology,MOE Frontiers Center for Brain Science,Fudan University,Shanghai,201508,China
3.Department of Neurosurgery,Huashan Hospital,Fudan University,Shanghai,200040,China
4.Department of Orthopedics,The Third Affiliated Hospital of Jinzhou Medical University,Jinzhou,Liaoning,121012,China
5.Department of Laboratory Animal Science,MOE Frontiers Center for Brain Science,Fudan University,Shanghai,200032,China
6.Shanghai Key Laboratory of Psychotic Disorders,Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai,201108,China
7.Shanghai Frontiers Science Center of Genome Editing and Cell Therapy,Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences,East China Normal University,Shanghai,200241,China
8.School of Life Sciences,Department of Biology,Shenzhen Key Laboratory of Gene Regulation and Systems Biology,Brain Research Center,Southern University of Science and Technology,Shenzhen,Guangdong,518055,China
9.Institute of Life Science,Nanchang University,Nanchang,Jiangxi,330031,China
10.Co-Innovation Center of Neuroregeneration,Nantong University,Nantong,Jiangsu,226001,China

Zhou, Tian,Li, Yuxin,Li, Xiaoyu,et al. Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice[J]. Nature Communications,2022,13(1).

Zhou, Tian.,Li, Yuxin.,Li, Xiaoyu.,Zeng, Fanzhuo.,Rao, Yanxia.,...&Peng, Bo.(2022).Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice.Nature Communications,13(1).

Zhou, Tian,et al."Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice".Nature Communications 13.1(2022).