A Neutral FeCl3 Photocatalysis for C-C Bond Animation and Alkylation of Cyclic Alcohols

Zhang, Zongnan1; Xue, Ting1; Han, Zhe2; Zeng, Rong1,3

2022-11-01

10.1055/a-1966-3271

SYNTHESIS-STUTTGART   影响因子和分区

0039-7881

1437-210X

A modified method for iron-catalyzed C-C bond cleavage and amination and alkylation of nonactivated cyclic alcohols has been developed. Using FeCl3 as catalyst, the photoinduced ligand-to-metal charge transfer facilitates the generation of O-radicals from alcohols, the subsequent beta-scission, and finally the radical trapping. Compared with the Fe(OR)(3) catalysis, this mildly base-free system could enable the amination in a broader substrate scope with higher yields. Moreover, the C-C bond cleavage and alkylation of cyclic alcohols proceeds with electron-deficient olefins under these conditions.

iron catalysis photocatalysis C-C bond cleavage amination alkylation

SCI ; EI ; IC ; CCR

英语

通讯

Guangdong Provincial Key Laboratory of Catalysis[21901197] ; [2020B121201002]

Chemistry

Chemistry, Organic

WOS:000890901300001

GEORG THIEME VERLAG KG

20230313400609

Alkylation ; Amination ; Amines ; Catalysis ; Chlorine compounds ; Iron ; Iron compounds

Iron:545.1 ; Chemical Reactions:802.2 ; Organic Compounds:804.1

CHEMISTRY

Web of Science

1.Xi An Jiao Tong Univ, Sch Chem, Xian 710049, Peoples R China
2.Xi An Jiao Tong Univ, Sch Nucl Sci & Technol, Xian 710049, Peoples R China
3.Southern Univ Sci & Technol, Guangdong Prov Key Lab Catalysis, Shenzhen 518055, Guangdong, Peoples R China

Zhang, Zongnan,Xue, Ting,Han, Zhe,et al. A Neutral FeCl3 Photocatalysis for C-C Bond Animation and Alkylation of Cyclic Alcohols[J]. SYNTHESIS-STUTTGART,2022,55(3):433-442.

Zhang, Zongnan,Xue, Ting,Han, Zhe,&Zeng, Rong.(2022).A Neutral FeCl3 Photocatalysis for C-C Bond Animation and Alkylation of Cyclic Alcohols.SYNTHESIS-STUTTGART,55(3),433-442.

Zhang, Zongnan,et al."A Neutral FeCl3 Photocatalysis for C-C Bond Animation and Alkylation of Cyclic Alcohols".SYNTHESIS-STUTTGART 55.3(2022):433-442.