Nanomaterials for the theranostics of obesity

Li, Juanjuan1,2; Cha, Ruitao1,2; Luo, Huize1,2; Hao, Wenshuai1,2; Zhang, Yan3,4; Jiang, Xingyu1,2,5,6

2019-12

10.1016/j.biomaterials.2019.119474

BIOMATERIALS   影响因子和分区

0142-9612

1878-5905

As a chronic and lifelong disease, obesity not only significant impairs health but also dramatically shortens life span (at least 10 years). Obesity requires a life-long effort for the successful treatment because a number of abnormalities would appear in the development of obesity. Nanomaterials possess large specific surface area, strong absorptivity, and high bioavailability, especially the good targeting properties and adjustable release rate, which would benefit the diagnosis and treatment of obesity and obesity-related metabolic diseases. Herein, we discussed the therapy and diagnosis of obesity and obesity-related metabolic diseases by using nanomaterials. Therapies of obesity with nanomaterials include improving intestinal health and reducing energy intake, targeting and treating functional cell abnormalities, regulating redox homeostasis, and removing free lipoprotein in blood. Diagnosis of obesity-related metabolic diseases would benefit the therapy of these diseases. The development of nanomaterials will promote the diagnosis and therapy of obesity and obesity-related metabolic diseases.

Nanomaterials Obesity Nanocellulose Adipocyte

SCI ; EI

英语

通讯

Haidian District of Beijing[255-kjc-020]

Engineering ; Materials Science

Engineering, Biomedical ; Materials Science, Biomaterials

WOS:000491303800016

ELSEVIER SCI LTD

20193807445567

Artificial life ; Biochemistry ; Diagnosis ; Disease control ; Metabolism ; Nanocellulose ; Nanostructured materials

Medicine and Pharmacology:461.6 ; Health Care:461.7 ; Nanotechnology:761 ; Biochemistry:801.2

MATERIALS SCIENCE

Web of Science

1.Beijing Engn Res Ctr BioNanotechnol, 11 Zhongguancun Beiyitiao, Beijing 100190, Peoples R China
2.Natl Ctr NanoSci & Technol, CAS Key Lab Biomed Effects Nanomat & Nanosafety, CAS Ctr Excellence Nanosci, 11 Zhongguancun Beiyitiao, Beijing 100190, Peoples R China
3.Chinese Acad Med Sci, Dept Cardiac Surg, State Key Lab Cardiovasc Dis, Fuwai Hosp,Natl Ctr Cardiovasc Dis, 167 North Lishi Rd, Beijing 100032, Peoples R China
4.Peking Union Med Coll, 167 North Lishi Rd, Beijing 100032, Peoples R China
5.Southern Univ Sci & Technol, Dept Biomed Engn, 1088 Xueyuan Rd, Shenzhen 518055, Guangdong, Peoples R China
6.Univ Chinese Acad Sci, 19 A Yuquan Rd, Beijing 100049, Peoples R China

Li, Juanjuan,Cha, Ruitao,Luo, Huize,et al. Nanomaterials for the theranostics of obesity[J]. BIOMATERIALS,2019,223.

Li, Juanjuan,Cha, Ruitao,Luo, Huize,Hao, Wenshuai,Zhang, Yan,&Jiang, Xingyu.(2019).Nanomaterials for the theranostics of obesity.BIOMATERIALS,223.

Li, Juanjuan,et al."Nanomaterials for the theranostics of obesity".BIOMATERIALS 223(2019).