南方科技大学知识苑(SUSTech KC): Organocatalytic oxa-Michael/Michael Addition/Deformylation Cascade Reaction of 3-Formylchromone with p-Quinol: Synthesis of the Furanochromanone Skeleton

题名	Organocatalytic oxa-Michael/Michael Addition/Deformylation Cascade Reaction of 3-Formylchromone with p-Quinol: Synthesis of the Furanochromanone Skeleton
作者	Zheng, Xiurong 1; Chen, Jiajia 1; Li, Zhuowen 1; Zhong, Lin 1; Zhan, Ruoting 1; Huang, Huicai 1,2
通讯作者	Huang, Huicai
发表日期	2022-12-01
DOI	10.1002/adsc.202201145
发表期刊	ADVANCED SYNTHESIS & CATALYSIS 影响因子和分区
ISSN	1615-4150
EISSN	1615-4169
摘要	An approach for the construction of furanochromanone skeletons has been developed through a DABCO-catalyzed cascade reaction with good yields (up to 83%) and high diastereoselectivity (> 20:1 dr). Notably, the asymmetric catalytic version of this reaction was further studied, obtaining furanochromanones bearing four contiguous stereogenic centers with excellent enantio- and diastereoselectivity (up to 98% ee, > 20:1 dr). This protocol causes the formation of a variety of substituted furanochromanones via an oxaMichael/Michael addition/deformylation cascade reaction.
关键词	cascade reaction furanochromanone skeleton asymmetric reaction deformylation p-quinol
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	通讯
资助项目	[22001048] ; [2017GC010361] ; [202102020215] ; [2020B121201002]
WOS研究方向	Chemistry
WOS类目	Chemistry, Applied ; Chemistry, Organic
WOS记录号	WOS:000897802200001
出版者	WILEY-V C H VERLAG GMBH
来源库	Web of Science
引用统计	被引频次[WOS]：4
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/420820
专题	南方科技大学
作者单位	1.Guangzhou Univ Chinese Med, Sch Pharmaceut Sci, Key Lab Chinese Med Resource Lingnan, Minist Educ, Guangzhou 510006, Peoples R China 2.Southern Univ Sci & Technol, Guangdong Prov Key Lab Catalysis, Shenzhen, Peoples R China
通讯作者单位	南方科技大学
推荐引用方式 GB/T 7714	Zheng, Xiurong,Chen, Jiajia,Li, Zhuowen,et al. Organocatalytic oxa-Michael/Michael Addition/Deformylation Cascade Reaction of 3-Formylchromone with p-Quinol: Synthesis of the Furanochromanone Skeleton[J]. ADVANCED SYNTHESIS & CATALYSIS,2022.
APA	Zheng, Xiurong,Chen, Jiajia,Li, Zhuowen,Zhong, Lin,Zhan, Ruoting,&Huang, Huicai.(2022).Organocatalytic oxa-Michael/Michael Addition/Deformylation Cascade Reaction of 3-Formylchromone with p-Quinol: Synthesis of the Furanochromanone Skeleton.ADVANCED SYNTHESIS & CATALYSIS.
MLA	Zheng, Xiurong,et al."Organocatalytic oxa-Michael/Michael Addition/Deformylation Cascade Reaction of 3-Formylchromone with p-Quinol: Synthesis of the Furanochromanone Skeleton".ADVANCED SYNTHESIS & CATALYSIS (2022).