南方科技大学知识苑(SUSTech KC): Gold(I)-Catalyzed and Ligand-Controlled Regioselective Cascade Cycloisomerizations of Bis(indolyl)-1,3-diynes and a Mechanistic Explanation

题名	Gold(I)-Catalyzed and Ligand-Controlled Regioselective Cascade Cycloisomerizations of Bis(indolyl)-1,3-diynes and a Mechanistic Explanation
作者	Zhang, Yan-Yan 1; Wei, Yin 1; Shi, Min1,2
通讯作者	Shi, Min
发表日期	2019-10-04
DOI	10.1021/acs.orglett.9b02778
发表期刊	ORGANIC LETTERS 影响因子和分区
ISSN	1523-7060
EISSN	1523-7052
卷号	21 期号:19页码:7799-7803
摘要	A regioselective synthetic method for the preparation of indole-fused seven-membered rings and bis(indole) connected to five-membered heterocyclic units from gold(I)-catalyzed cascade cycloisomerization of bis(indolyl)-1,3-diynes is described. This divergence in product selectivity was induced by introducing another alkynyl moiety to change the electron density at the internal alkyne and fine-tuning the steric nature of the phosphine ligand in the Au(I) catalyst. Mechanistic studies including DFT calculations uncovered the ligand-controlled manner.
相关链接	[来源记录]
收录类别	SCI ; IC ; CCR
语种	英语
重要成果	NI期刊
学校署名	通讯
资助项目	National Natural Science Foundation of China[20472096] ; National Natural Science Foundation of China[21372241] ; National Natural Science Foundation of China[21572052] ; National Natural Science Foundation of China[20672127] ; National Natural Science Foundation of China[21421091] ; National Natural Science Foundation of China[21372250] ; National Natural Science Foundation of China[21121062] ; National Natural Science Foundation of China[21302203] ; National Natural Science Foundation of China[21772226] ; National Natural Science Foundation of China[20732008] ; National Natural Science Foundation of China[21772037] ; National Natural Science Foundation of China[21861132014]
WOS研究方向	Chemistry
WOS类目	Chemistry, Organic
WOS记录号	WOS:000489200100025
出版者	AMER CHEMICAL SOC
ESI学科分类	CHEMISTRY
来源库	Web of Science
引用统计	被引频次[WOS]：7
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/42132
专题	深圳格拉布斯研究院
作者单位	1.Univ Chinese Acad Sci, Ctr Excellence Mol Synth, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, 345 Ling Ling Lu, Shanghai 200032, Peoples R China 2.Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen 518000, Guangdong, Peoples R China
通讯作者单位	深圳格拉布斯研究院
推荐引用方式 GB/T 7714	Zhang, Yan-Yan,Wei, Yin,Shi, Min. Gold(I)-Catalyzed and Ligand-Controlled Regioselective Cascade Cycloisomerizations of Bis(indolyl)-1,3-diynes and a Mechanistic Explanation[J]. ORGANIC LETTERS,2019,21(19):7799-7803.
APA	Zhang, Yan-Yan,Wei, Yin,&Shi, Min.(2019).Gold(I)-Catalyzed and Ligand-Controlled Regioselective Cascade Cycloisomerizations of Bis(indolyl)-1,3-diynes and a Mechanistic Explanation.ORGANIC LETTERS,21(19),7799-7803.
MLA	Zhang, Yan-Yan,et al."Gold(I)-Catalyzed and Ligand-Controlled Regioselective Cascade Cycloisomerizations of Bis(indolyl)-1,3-diynes and a Mechanistic Explanation".ORGANIC LETTERS 21.19(2019):7799-7803.