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题名

Enantioselective construction of 3-substituted 3-amino-2-oxindoles containing an N,N-ketal skeleton via organocatalyzed aza-addition of isatin imines

作者
通讯作者Li, Pengfei; Li, Wenjun
发表日期
2019-09-28
DOI
发表期刊
ISSN
1477-0520
EISSN
1477-0539
卷号17期号:36页码:8374-8378
摘要
The first example of organocatalytic chemo-, regio- and enantioselective aza-Mannich reactions of triazoles and arylamines, respectively, with isatin-derived imines has been achieved in the presence of double hydrogen bonding organocatalysts, affording the valuable optically active 3-substituted 3-amino-2-oxindoles featuring N,N-ketal structural motifs in high yields. This strategy was featured by low catalyst loading, mild conditions, broad substrate scope, and high efficiency and selectivity.
相关链接[来源记录]
收录类别
SCI ; EI ; IC ; CCR
语种
英语
学校署名
通讯
资助项目
Shenzhen Innovation of Science and Technology Commission[JCYJ20170817110526264] ; Shenzhen Innovation of Science and Technology Commission[ZDSYS201802081843490]
WOS研究方向
Chemistry
WOS类目
Chemistry, Organic
WOS记录号
WOS:000487021800009
出版者
EI入藏号
20193907465606
EI主题词
Enantioselectivity ; Hydrogen bonds
EI分类号
Physical Chemistry:801.4 ; Chemical Agents and Basic Industrial Chemicals:803 ; Chemical Products Generally:804
ESI学科分类
CHEMISTRY
来源库
Web of Science
引用统计
被引频次[WOS]:9
成果类型期刊论文
条目标识符http://sustech.caswiz.com/handle/2SGJ60CL/42180
专题理学院_化学系
作者单位
1.Qingdao Univ, Sch Pharm, Dept Med Chem, Qingdao 266021, Shandong, Peoples R China
2.Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China
3.Southern Univ Sci & Technol, Shenzhen Key Lab Marine Archaea Geoomics, Shenzhen 518055, Peoples R China
通讯作者单位化学系;  南方科技大学
推荐引用方式
GB/T 7714
Zhang, Chen,Shang, Xinye,Cheng, Yuyu,et al. Enantioselective construction of 3-substituted 3-amino-2-oxindoles containing an N,N-ketal skeleton via organocatalyzed aza-addition of isatin imines[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2019,17(36):8374-8378.
APA
Zhang, Chen.,Shang, Xinye.,Cheng, Yuyu.,Li, Fushuai.,Zhao, Hanhui.,...&Li, Wenjun.(2019).Enantioselective construction of 3-substituted 3-amino-2-oxindoles containing an N,N-ketal skeleton via organocatalyzed aza-addition of isatin imines.ORGANIC & BIOMOLECULAR CHEMISTRY,17(36),8374-8378.
MLA
Zhang, Chen,et al."Enantioselective construction of 3-substituted 3-amino-2-oxindoles containing an N,N-ketal skeleton via organocatalyzed aza-addition of isatin imines".ORGANIC & BIOMOLECULAR CHEMISTRY 17.36(2019):8374-8378.
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