南方科技大学知识苑(SUSTech KC): Whether jugular venous reflux relates to more serious ischemic white matter lesions?

题名	Whether jugular venous reflux relates to more serious ischemic white matter lesions?
作者	Zhang, Hui 1,2 ; Deng, Jian 1,2; He, Yibo 1,2; Guo, Yi 1,2; He, Yitao 1,2,3
通讯作者	He, Yitao
发表日期	2023-02-01
DOI	10.1016/j.clineuro.2022.107582
发表期刊	CLINICAL NEUROLOGY AND NEUROSURGERY 影响因子和分区
ISSN	0303-8467
EISSN	1872-6968
卷号	225
摘要	Objective: To evaluate whether jugular venous reflux (JVR) relates to more serious ischemic white matter lesions (WMLs).Patients and Methods: Fifty cases were enrolled and divided into absent to mild ischemic WMLs group and moderate to severe ischemic WMLs group. Then the univariate and multivariate analyses were conducted to evaluate the relationship between JVR and moderate to severe ischemic WMLs, and a receiver operating characteristic (ROC) curve was used to evaluate the predictive value of JVR for moderate to severe ischemic WMLs.Results: There were 28 patients in the absent to mild ischemic WMLs group and 22 patients in the moderate to severe ischemic WMLs group. There was no significant difference between the two groups in gender, blood lipid indexes, proportions of diabetes, and abnormal deep cerebral veins (all p > 0.05). However, compared with the absent to mild ischemic WMLs group, the moderate to severe ischemic WMLs group was older and had a higher proportion of hypertension and JVR (p = 0.005; p < 0.001; p < 0.001, respectively). Multivariate logistic regression analysis showed that JVR was an independent risk factor for moderate to severe ischemic WMLs (OR = 17.679, 95 % CI: 3.056-102.286, p = 0.001). Furthermore, the area under curve of JVR combined with hypertension was 0.912 (p < 0.001), and the specificity of predicting moderate to severe ischemic WMLs was 92.9 %.Conclusion: Our study suggested that JVR might relate to more severe ischemic WMLs.
关键词	Jugular venous reflux Ischemic white matter lesions Hypertension Age
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	通讯
资助项目	National Natural Science Foundation of China[82071463] ; Shenzhen People's Hospital[SYLCYJ202117]
WOS研究方向	Neurosciences & Neurology ; Surgery
WOS类目	Clinical Neurology ; Surgery
WOS记录号	WOS:000919655600001
出版者	ELSEVIER
ESI学科分类	CLINICAL MEDICINE
来源库	Web of Science
引用统计	被引频次[WOS]：0
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/430745
专题	南方科技大学第一附属医院
作者单位	1.Jinan Univ, Dept Neurol, Clin Med Coll 2, Shenzhen, Guangdong, Peoples R China 2.Southern Univ Sci & Technol, Shenzhen Peoples Hosp, Affiliated Hosp 1, Dept Neurol, Shenzhen, Guangdong, Peoples R China 3.1017,Dongmen North Rd, Shenzhen, Guangdong, Peoples R China
第一作者单位	南方科技大学第一附属医院
通讯作者单位	南方科技大学第一附属医院
推荐引用方式 GB/T 7714	Zhang, Hui,Deng, Jian,He, Yibo,et al. Whether jugular venous reflux relates to more serious ischemic white matter lesions?[J]. CLINICAL NEUROLOGY AND NEUROSURGERY,2023,225.
APA	Zhang, Hui,Deng, Jian,He, Yibo,Guo, Yi,&He, Yitao.(2023).Whether jugular venous reflux relates to more serious ischemic white matter lesions?.CLINICAL NEUROLOGY AND NEUROSURGERY,225.
MLA	Zhang, Hui,et al."Whether jugular venous reflux relates to more serious ischemic white matter lesions?".CLINICAL NEUROLOGY AND NEUROSURGERY 225(2023).