Determination of newly synthesized dihydroxylated polybrominated diphenyl ethers in sea fish by gas chromatography-tandem mass spectrometry

Zhang，Mengtao1,2; Guo，Wei1; Wei，Juntong2; Shi，Jianghong1; Zhang，Jiawei1; Ge，Hui1; Tao，Huanyu1; Liu，Xiaowei3; Hu，Qing1; Cai，Zongwei2

2020-02-01

10.1016/j.chemosphere.2019.124878

CHEMOSPHERE   影响因子和分区

0045-6535

1879-1298

Dihydroxylated polybrominated diphenyl ethers (diOH-PBDEs) can be natural products of marine organisms or the metabolites of PBDEs. The optimal determination method and concentration of diOH-PBDEs in seafood are unknown due to a lack of commercially available standards. In the present study, diOH-PBDEs were synthesized, and an efficient measurement method for OH-PBDEs and diOH-PBDEs in sea fish muscle samples, including extraction, clean-up and gas chromatography-tandem mass spectrometry (GC-MS/MS) analysis, was established. Pressurized liquid extraction (PLE) followed by partitioning with a KOH solution and florisil cartridge clean-up proved to be a reliable and robust method for detecting all OH-PBDEs/diOH-PBDEs. GC-MS/MS with an electron ionization (EI) source analysis was a sensitive analytical instrument for OH-PBDEs/diOH-PBDEs. The recovery using this method ranged from 19% to 101%, 28%–88% and 42%–90% for 10 ng, 20 ng and 40 ng spiking levels, respectively. The equipment detection limits (EDLs) were in the range of 0.31–2.78 pg/μL, and the limits of detection (LOD) for the method were in the range of 5.07–38.74 pg/g wet weight. Concentrations of diOH-PBDEs in the marine fish muscle samples were in the range of 32.43–1528.63 pg/g wet weight. Similar compositions of OH-PBDEs/diOH-PBDEs were found within the same family of marine fish.

DiOH-PBDEs Fish muscle GC-MS/MS OH-PBDEs Pressurized liquid extraction

SCI ; EI

英语

第一 ; 通讯

Guangdong Provincial Key Laboratory of Soil and Groundwater Pollution Control[2017B030301012]

Environmental Sciences & Ecology

Environmental Sciences

WOS:000497600800022

PERGAMON-ELSEVIER SCIENCE LTD

20193907472748

Ethers ; Extraction ; Fish ; Gas chromatography ; Ionization of gases ; Marine biology ; Mass spectrometry ; Muscle ; Potassium hydroxide

Biological Materials and Tissue Engineering:461.2 ; Biology:461.9 ; Chemistry:801 ; Chemical Reactions:802.2 ; Chemical Operations:802.3 ; Organic Compounds:804.1 ; Inorganic Compounds:804.2

ENVIRONMENT/ECOLOGY

2-s2.0-85072580004

Scopus

1.State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution ControlSchool of Environmental Science and EngineeringSouthern University of Science and Technology,Shenzhen,518055,China
2.China State Key Laboratory of Environmental and Biological AnalysisDepartment of ChemistryHong Kong Baptist University,Hong Kong
3.Hefei University of Technology (Xuancheng Campus) Xuancheng,China

Zhang，Mengtao,Guo，Wei,Wei，Juntong,et al. Determination of newly synthesized dihydroxylated polybrominated diphenyl ethers in sea fish by gas chromatography-tandem mass spectrometry[J]. CHEMOSPHERE,2020,240.

Zhang，Mengtao.,Guo，Wei.,Wei，Juntong.,Shi，Jianghong.,Zhang，Jiawei.,...&Cai，Zongwei.(2020).Determination of newly synthesized dihydroxylated polybrominated diphenyl ethers in sea fish by gas chromatography-tandem mass spectrometry.CHEMOSPHERE,240.

Zhang，Mengtao,et al."Determination of newly synthesized dihydroxylated polybrominated diphenyl ethers in sea fish by gas chromatography-tandem mass spectrometry".CHEMOSPHERE 240(2020).