南方科技大学知识苑(SUSTech KC): Photoswitchable hemithioindigo inspired copper ion selective sensing with excellent selectivity and versatile operational modes

题名	Photoswitchable hemithioindigo inspired copper ion selective sensing with excellent selectivity and versatile operational modes
作者	Chen，Qinghan1,2 ; Wang，Yifu2 ; Zhai，Jingying3,4 ; Xie，Xiaojiang2,4
通讯作者	Zhai，Jingying
发表日期	2023-04-15
DOI	10.1016/j.snb.2023.133437
发表期刊	SENSORS AND ACTUATORS B-CHEMICAL 影响因子和分区
ISSN	0925-4005
EISSN	0925-4005
卷号	381
摘要	Copper is an essential element in living organisms and the monitoring of copper ions in aquatic environments and biological systems is of great significance. Inspired by a family of visible light responsive photoswitchable compounds, we report here a fluorescent probe (HTI-Q) for Cu with excellent selectivity, high sensitivity, and a limit of detection (LOD) of ca. 0.02 μM. While the central carbon-carbon double bond of HTI-Q is photoisomerizable between the Z and E configurations, it is locked upon binding with Cu into the E configuration, resulting in a large bathochromic shift (102 nm) and ratiometric fluorescence changes. Different sensing modes were demonstrated including in mixed solvents, a two-phase sensing system containing cation exchanger, and fluorescent nanoprobes containing a reference dye. The absorbance change of HTI-Q upon 470 nm light illumination also depended on the concentration of Cu. HTI-Q-based sensors were successfully applied to determine Cu in real water samples with excellent recovery. Further, fluorescent nanoprobes incorporating HTI-Q were successfully applied to image endolysosomal Cu changes upon external stimulation.
关键词	Cell imaging Copper Fluorescent probe Hemithioindigo Lysosomes Photoswitch
相关链接	[Scopus记录]
收录类别	SCI ; EI
语种	英语
学校署名	通讯
资助项目	Department of Science and Technology of Guangdong Province[2021A1515010330] ; Na- tional Natural Science Foundation of China["21904059","22274070"] ; Guangdong Provincial Key Laboratory of Advanced Biomaterials[2022B1212010003]
WOS研究方向	Chemistry ; Electrochemistry ; Instruments & Instrumentation
WOS类目	Chemistry, Analytical ; Electrochemistry ; Instruments & Instrumentation
WOS记录号	WOS:000977965500001
出版者	ELSEVIER SCIENCE SA
EI入藏号	20230513493299
EI主题词	Aquatic organisms ; Carbon ; Fluorescence ; Metal ions ; Nanoprobes ; Probes
EI分类号	Marine Science and Oceanography:471 ; Metallurgy:531.1 ; Copper:544.1 ; Light/Optics:741.1 ; Optical Devices and Systems:741.3 ; Nanotechnology:761 ; Chemical Products Generally:804 ; Solid State Physics:933
ESI学科分类	CHEMISTRY
Scopus记录号	2-s2.0-85147122392
来源库	Scopus
引用统计	被引频次[WOS]：21
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/442582
专题	理学院_化学系前沿与交叉科学研究院
作者单位	1.School of Chemistry and Chemical Engineering,Harbin Institute of Technology,Harbin,150001,China 2.Department of Chemistry,Southern University of Science and Technology,Shenzhen,518055,China 3.Academy for Advanced Interdisciplinary Studies,Southern University of Science and Technology,Shenzhen,518055,China 4.Guangdong Provincial Key Laboratory of Advanced Biomaterials,Southern University of Science and Technology,Shenzhen,518055,China
第一作者单位	化学系
通讯作者单位	前沿与交叉科学研究院; 南方科技大学
推荐引用方式 GB/T 7714	Chen，Qinghan,Wang，Yifu,Zhai，Jingying,et al. Photoswitchable hemithioindigo inspired copper ion selective sensing with excellent selectivity and versatile operational modes[J]. SENSORS AND ACTUATORS B-CHEMICAL,2023,381.
APA	Chen，Qinghan,Wang，Yifu,Zhai，Jingying,&Xie，Xiaojiang.(2023).Photoswitchable hemithioindigo inspired copper ion selective sensing with excellent selectivity and versatile operational modes.SENSORS AND ACTUATORS B-CHEMICAL,381.
MLA	Chen，Qinghan,et al."Photoswitchable hemithioindigo inspired copper ion selective sensing with excellent selectivity and versatile operational modes".SENSORS AND ACTUATORS B-CHEMICAL 381(2023).