I2-DMSO-H2O: A Metal-Free Combination System for the Oxidative Addition of Alkynes to Access (E)-alpha-Iodo-beta-methylsulfonylalkenes.

Zhou, Peng; Pan, Yupeng*; Tan, Hua; Liu, Weibing

2019-10-30

10.1021/acs.joc.9b02302

JOURNAL OF ORGANIC CHEMISTRY   影响因子和分区

0022-3263

1520-6904

A simple and green reaction was discovered for iodization-methylsulfoxidation of alkynes to access (E)-alpha-iodo-beta-methylsulfonylalkenes. This is the first report for the synthesis of iodovinyl methylsulfones by employing alkynes to react with molecular iodine (I-2), dimethyl sulfoxide (DMSO), and H2O. Additionally, this protocol represents a new avenue for utilizing DMSO as the source of the -SO2Me group and H2O as the "O" source for the construction of the -SO2Me group from DMSO, which is a valuable finding.

SCIE ; SCI ; IC ; CCR ; EI

英语

其他

Guangdong Natural Science Foundation[2017A030307006]

Chemistry

Chemistry, Organic

WOS:000502170600062

AMER CHEMICAL SOC

20194707711654

Dimethyl sulfoxide ; Hydrocarbons

Organic Compounds:804.1

CHEMISTRY

Web of Science

Zhou, Peng,Pan, Yupeng*,Tan, Hua,et al. I2-DMSO-H2O: A Metal-Free Combination System for the Oxidative Addition of Alkynes to Access (E)-alpha-Iodo-beta-methylsulfonylalkenes.[J]. JOURNAL OF ORGANIC CHEMISTRY,2019,84(23):15662-15668.

Zhou, Peng,Pan, Yupeng*,Tan, Hua,&Liu, Weibing.(2019).I2-DMSO-H2O: A Metal-Free Combination System for the Oxidative Addition of Alkynes to Access (E)-alpha-Iodo-beta-methylsulfonylalkenes..JOURNAL OF ORGANIC CHEMISTRY,84(23),15662-15668.

Zhou, Peng,et al."I2-DMSO-H2O: A Metal-Free Combination System for the Oxidative Addition of Alkynes to Access (E)-alpha-Iodo-beta-methylsulfonylalkenes.".JOURNAL OF ORGANIC CHEMISTRY 84.23(2019):15662-15668.