南方科技大学知识苑(SUSTech KC): Differential antigen expression between human apocrine sweat glands and eccrine sweat glands

题名	Differential antigen expression between human apocrine sweat glands and eccrine sweat glands
作者	Cao, Manxiu 1; Zhang, Lei2 ; Cheng, Jiaqi 1; Wang, Cangyu 1; Zhao, Junhong 1; Liu, Xiang 1; Yan, Yongjing 1; Tang, Yue 1; Chen, Zixiu 1; Li, Haihong 1,3,4
通讯作者	Li, Haihong
发表日期	2023
DOI	10.4081/ejh.2023.3559
发表期刊	EUROPEAN JOURNAL OF HISTOCHEMISTRY 影响因子和分区
ISSN	1121-760X
EISSN	2038-8306
卷号	67 期号:1
摘要	Bromhidrosis has a great negative impact on personal occupation and social psychology. It is not yet clear whether bromhidrosis is caused by apocrine sweat glands or the co-action of apocrine sweat glands and eccrine sweat glands. To distinguish between apocrine sweat glands and eccrine sweat glands, specific antigen markers for apocrine sweat glands and eccrine sweat glands must be found first. In the study, we detected the expression of keratin (K) 7, K18, K19, Na+-K+-2Cl- cotransporter 1 (NKCC1), carbonic anhydrase II (CAII), Forkhead transcription factor a1 (Foxa1), homeobox transcription factor engrailed homeobox1 (En1), gross cystic disease fluid protein-15 (GCDFP-15), mucin-1 (MUC-1), cluster of differentiation 15 (CD15) and apolipoprotein (APOD) in eccrine sweat glands and apocrine sweat glands by immunofluorescence staining. The results showed that K7, K18, K19, Foxa1, GCDFP-15 and MUC-1 were expressed in both apocrine and eccrine sweat glands, CD15 and APOD were only expressed in apocrine sweat glands, and CAII, NKCC1 and En1 were only expressed in eccrine sweat glands. We conclude that CD15 and APOD can serve as specific markers for apoc-rine sweat glands, while CAII, NKCC1 and En1 can serve as specific markers for eccrine sweat glands to dif-ferentiate the two sweat glands.
关键词	Apocrine sweat glands eccrine sweat glands human differential markers immunofluorescence
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	通讯
资助项目	null[82172231] ; null[82172211] ; null[81830064]
WOS研究方向	Cell Biology
WOS类目	Cell Biology
WOS记录号	WOS:000921292300003
出版者	PAGEPRESS PUBL
ESI学科分类	BIOLOGY & BIOCHEMISTRY
来源库	Web of Science
引用统计	被引频次[WOS]：2
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/475011
专题	南方科技大学医学院南方科技大学医院
作者单位	1.Hubei Univ Med, Taihe Hosp, Dept Wound Repair & Dermatol Surg, Shiyan, Hubei, Peoples R China 2.Southern Univ Sci & Technol, Dept Mental Hlth, Southern Univ Sci & Technol Hosp, Sch Med, Shenzhen, Guangdong, Peoples R China 3.Southern Univ Sci & Technol, Sch Med, Dept Wound Repair, Inst Wound Repair & Regenerat Med,Southern Univ Sc, Shenzhen, Guangdong, Peoples R China 4.Hubei Univ Med, Taihe Hosp, Dept Wound Repair & Dermatol Surg, 32 South Renmin Rd, Shiyan 442000, Hubei, Peoples R China
通讯作者单位	南方科技大学医学院
推荐引用方式 GB/T 7714	Cao, Manxiu,Zhang, Lei,Cheng, Jiaqi,et al. Differential antigen expression between human apocrine sweat glands and eccrine sweat glands[J]. EUROPEAN JOURNAL OF HISTOCHEMISTRY,2023,67(1).
APA	Cao, Manxiu.,Zhang, Lei.,Cheng, Jiaqi.,Wang, Cangyu.,Zhao, Junhong.,...&Li, Haihong.(2023).Differential antigen expression between human apocrine sweat glands and eccrine sweat glands.EUROPEAN JOURNAL OF HISTOCHEMISTRY,67(1).
MLA	Cao, Manxiu,et al."Differential antigen expression between human apocrine sweat glands and eccrine sweat glands".EUROPEAN JOURNAL OF HISTOCHEMISTRY 67.1(2023).