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题名

Novel roles of RNA-binding proteins in drug resistance of breast cancer: from molecular biology to targeting therapeutics

作者
通讯作者Yao, Herui; Gong, Chang
发表日期
2023-02-09
DOI
发表期刊
EISSN
2058-7716
卷号9期号:1
摘要
Therapy resistance remains a huge challenge for current breast cancer treatments. Exploring molecular mechanisms of therapy resistance might provide therapeutic targets for patients with advanced breast cancer and improve their prognosis. RNA-binding proteins (RBPs) play an important role in regulating therapy resistance. Here we summarize the functions of RBPs, highlight their tremendously important roles in regulating therapy sensitivity and resistance and we also reveal current therapeutic approaches reversing abnormal functions of RBPs in breast cancer.
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语种
英语
学校署名
其他
资助项目
Natural Science Foundation of China["81872139","82072907"] ; Project of The Beijing Xisike Clinical Oncology Research Foundation[Y-Roche2019/2-0078\Y-pierrefabre202102-0107] ; Technology Development Program of Guangdong province[2021A0505030082] ; Project of The Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation[2020B1212060018] ; null[2022005]
WOS研究方向
Cell Biology
WOS类目
Cell Biology
WOS记录号
WOS:000931464000001
出版者
来源库
Web of Science
引用统计
被引频次[WOS]:12
成果类型期刊论文
条目标识符http://sustech.caswiz.com/handle/2SGJ60CL/489978
专题南方科技大学第一附属医院
作者单位
1.Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangdong Prov Key Lab Malignant Tumor Epigenet &, Guangzhou 510120, Peoples R China
2.Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Breast Tumor Ctr, Guangzhou 510120, Peoples R China
3.Jinan Univ, Southern Univ Sci & Technol, Shenzhen Peoples Hosp, Affiliated Hosp 1,Dept Breast & Thyroid Surg,Clin, Shenzhen 518020, Peoples R China
推荐引用方式
GB/T 7714
Cen, Yinghuan,Chen, Letian,Liu, Zihao,et al. Novel roles of RNA-binding proteins in drug resistance of breast cancer: from molecular biology to targeting therapeutics[J]. CELL DEATH DISCOVERY,2023,9(1).
APA
Cen, Yinghuan.,Chen, Letian.,Liu, Zihao.,Lin, Qun.,Fang, Xiaolin.,...&Gong, Chang.(2023).Novel roles of RNA-binding proteins in drug resistance of breast cancer: from molecular biology to targeting therapeutics.CELL DEATH DISCOVERY,9(1).
MLA
Cen, Yinghuan,et al."Novel roles of RNA-binding proteins in drug resistance of breast cancer: from molecular biology to targeting therapeutics".CELL DEATH DISCOVERY 9.1(2023).
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