| 题名 | Advances in Spheroids and Organoids on a Chip |
| 作者 | |
| 通讯作者 | Lu, Hongxu; Jin, Dayong |
| 发表日期 | 2023-02-01
|
| DOI | |
| 发表期刊 | |
| ISSN | 1616-301X
|
| EISSN | 1616-3028
|
| 卷号 | 33 |
| 摘要 | Multicellular spheroids and organoids are promising in vitro 3D models in personalized medicine and drug screening. They replicate the structural and functional characteristics of human organs in vivo. Microfluidic technology and micro-nano fabrication can fulfill the high requirement of the engineering approach in the growing research interest in spheroids and organoids. In this review, spheroids and organoids are comparatively introduced. Then it is illustrated how spheroids- and organoids-on-a-chip technology facilitates their establishment, expansion, and application through spatial-temporal control, mechanical cues modeling, high-throughput analysis, co-culture, multi-tissue interactions, biosensing, and bioimaging integration. The potential opportunities and challenges in developing spheroids- and organoids-on-a-chip technology are finally outlooked. |
| 关键词 | |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 学校署名 | 通讯
|
| 资助项目 | Major International (Regional) Joint Research Project of NSFC[51720105015]
; Science and Technology Innovation Commission of Shenzhen[KQTD20170810110913065]
; Australian Research Council Laureate Fellowship Program[FL210100180]
; Nanyang Presidential Fellowship Program[03INS001307C140]
|
| WOS研究方向 | Chemistry
; Science & Technology - Other Topics
; Materials Science
; Physics
|
| WOS类目 | Chemistry, Multidisciplinary
; Chemistry, Physical
; Nanoscience & Nanotechnology
; Materials Science, Multidisciplinary
; Physics, Applied
; Physics, Condensed Matter
|
| WOS记录号 | WOS:000936107600001
|
| 出版者 | |
| EI入藏号 | 20230913634294
|
| EI主题词 | Bioimaging
; Diagnosis
; Functional materials
|
| EI分类号 | Medicine and Pharmacology:461.6
; Microfluidics:632.5.1
; Imaging Techniques:746
; Materials Science:951
|
| ESI学科分类 | MATERIALS SCIENCE
|
| 来源库 | Web of Science
|
| 引用统计 |
被引频次[WOS]：36
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/490015 |
| 专题 | 工学院_生物医学工程系 |
| 作者单位 | 1.Nanyang Technol Univ, Sch Elect & Elect Engn, 50 Nanyang Ave, Singapore 639798, Singapore 2.Univ Technol Sydney, Inst Biomed Mat & Devices, Sch Math & Phys Sci, Broadway Ultimo, Sydney, NSW 2007, Australia 3.Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, State Key Lab High Performance Ceram & Superfine M, 1295 Dingxi Rd, Shanghai 200050, Peoples R China 4.Southern Univ Sci & Technol, Dept Biomed Engn, UTS SUSTech Joint Res Ctr Biomed Mat & Devices, Shenzhen 518055, Peoples R China |
| 通讯作者单位 | 生物医学工程系 |
| 推荐引用方式 GB/T 7714 |
Fang, Guocheng,Chen, Yu-Cheng,Lu, Hongxu,et al. Advances in Spheroids and Organoids on a Chip[J]. ADVANCED FUNCTIONAL MATERIALS,2023,33.
|
| APA |
Fang, Guocheng,Chen, Yu-Cheng,Lu, Hongxu,&Jin, Dayong.(2023).Advances in Spheroids and Organoids on a Chip.ADVANCED FUNCTIONAL MATERIALS,33.
|
| MLA |
Fang, Guocheng,et al."Advances in Spheroids and Organoids on a Chip".ADVANCED FUNCTIONAL MATERIALS 33(2023).
|
| 条目包含的文件 | 条目无相关文件。 | |||||
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