Long-Term Visit-To-Visit Blood Pressure Variability and Risk of Diabetes Mellitus in Chinese Population: A Retrospective Population-Based Study

Zhou, Rui1; Li, Fu-Rong1,2; Liu, Kuan1; Huang, Rui-Dian3; Liu, Hua-Min4; Yuan, Ze-Lin1; Zheng, Jia-Zhen5,6; Zou, Meng-Chen7; Wu, Xian-Bo1

2023-02-06

10.3389/ijph.2023.1605445

International Journal of Public Health   影响因子和分区

1661-8556

1661-8564

Objectives: To examine the association between visit-to-visit blood pressure variability (BPV) and incident diabetes mellitus (DM) risk in a Chinese population.Methods: Data comes from China Health and Nutrition Survey (n = 15,084). BPV was estimated as the average real variability (ARV) using at least three BP measurements from the year preceding the event and was divided into quartiles. Participants were also categorized into 9 groups on the basis of combinations of systolic BPV (SBPV) and diastolic BPV (DBPV) tertiles. Cox proportional hazards regression models were used.Results: During a median follow-up of 16.8 years, 1,030 (6.8%) participants developed diabetes (incidence rate: 4.65/1,000 person-years). The HRs (95% CIs) for the highest quartile (vs. the lowest quartile) of SBPV and DBPV were 1.60 (1.30-1.97) and 1.37 (1.13-1.67), respectively. Participants with both highest SBPV and DBPV tertile had an approximate to 89% higher risk of DM (HR, 1.89; 95% CI, 1.47-2.42) compared with those in the both SBPV and DBPV tertile 1 group.Conclusion: Higher SBP ARV and DBP ARV were independently associated with increased risk of incident DM, which was augmented when both presented together.

China diabetes mellitus blood pressure variability cohort

SCI ; SSCI

英语

其他

National Natural Science Foundation of China[82173607] ; Guangdong Basic and Applied Basic Research Foundation[2021A1515011684] ; Open Project of the Guangdong Provincial Key Laboratory of Tropical Disease Research[2020B1212060042] ; Guangzhou Science and Technology Project[202102080597]

Public, Environmental & Occupational Health

Public, Environmental & Occupational Health

WOS:000937650900001

FRONTIERS MEDIA SA

Web of Science

1.Southern Med Univ, Sch Publ Hlth, Dept Epidemiol, Guangdong Prov Key Lab Trop Dis Res, Guangzhou, Peoples R China
2.Southern Univ Sci & Technol, Sch Med, Shenzhen, Peoples R China
3.Hosp Zhongluotan, Publ Hlth Div, Guangzhou, Peoples R China
4.Southern Med Univ, Nanfang Hosp, Dept Anaesthesiol, Guangzhou, Peoples R China
5.Hong Kong Univ Sci & Technol Guangzhou, Biosci & Biomed Engn Thrust, Syst Hub, Guangzhou, Peoples R China
6.Hong Kong Univ Sci & Technol, Biosci & Biomed Engn Thrust, Syst Hub, Hong Kong, Peoples R China
7.Southern Med Univ, Nanfang Hosp, Dept Endocrinol & Metab, Guangzhou, Peoples R China

Zhou, Rui,Li, Fu-Rong,Liu, Kuan,et al. Long-Term Visit-To-Visit Blood Pressure Variability and Risk of Diabetes Mellitus in Chinese Population: A Retrospective Population-Based Study[J]. International Journal of Public Health,2023,68.

Zhou, Rui.,Li, Fu-Rong.,Liu, Kuan.,Huang, Rui-Dian.,Liu, Hua-Min.,...&Wu, Xian-Bo.(2023).Long-Term Visit-To-Visit Blood Pressure Variability and Risk of Diabetes Mellitus in Chinese Population: A Retrospective Population-Based Study.International Journal of Public Health,68.

Zhou, Rui,et al."Long-Term Visit-To-Visit Blood Pressure Variability and Risk of Diabetes Mellitus in Chinese Population: A Retrospective Population-Based Study".International Journal of Public Health 68(2023).