Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Kanoni, Stavroula1; Graham, Sarah E.2; Wang, Yuxuan3; Surakka, Ida2; Ramdas, Shweta4; Zhu, Xiang5,6,7,8; Clarke, Shoa L.7,9; Bhatti, Konain Fatima1; Vedantam, Sailaja10,11; Winkler, Thomas W.12; Locke, Adam E.13,14; Marouli, Eirini1; Zajac, Greg J. M.15; Wu, Kuan-Han H.16; Ntalla, Ioanna1; Hui, Qin17,18; Klarin, Derek7,19; Hilliard, Austin T.7; Wang, Zeyuan17,18; Xue, Chao2; Thorleifsson, Gudmar20; Helgadottir, Anna20; Gudbjartsson, Daniel F.20,21; Holm, Hilma20; Olafsson, Isleifur22; Hwang, Mi Yeong23; Han, Sohee23; Akiyama, Masato24,25; Sakaue, Saori24,26,27; Terao, Chikashi28; Kanai, Masahiro11,24,29; Zhou, Wei11,16,30; Brumpton, Ben M.31,32,33; Rasheed, Humaira31,32,34; Havulinna, Aki S.35,36; Veturi, Yogasudha37; Pacheco, Jennifer Allen38; Rosenthal, Elisabeth A.39; Lingren, Todd40; Feng, QiPing41; Kullo, Iftikhar J.42,43; Narita, Akira44; Takayama, Jun44; Martin, Hilary C.45; Hunt, Karen A.46; Trivedi, Bhavi46; Haessler, Jefrey47; Giulianini, Franco48; Bradford, Yuki37; Miller, Jason E.37; Campbell, Archie49,50; Lin, Kuang51,52; Millwood, Iona Y.51,52,53; Rasheed, Asif54; Hindy, George55; Faul, Jessica D.56; Zhao, Wei56,57; Weir, David R.56; Turman, Constance58; Huang, Hongyan58; Graf, Mariaelisa59; Choudhury, Ananyo60; Sengupta, Dhriti60; Mahajan, Anubha61; Brown, Michael R.62; Zhang, Weihua63,64; Yu, Ketian15; Schmidt, Ellen M.15; Pandit, Anita15; Gustafsson, Stefan65; Yin, Xianyong15; Luan, Jian'an66; Zhao, Jing-Hua67; Matsuda, Fumihiko68; Jang, Hye-Mi23; Yoon, Kyungheon23; Medina-Gomez, Carolina69; Pitsillides, Achilleas3; Hottenga, Jouke Jan70,71; Wood, Andrew R.72; Ji, Yingji72; Gao, Zishan73,74,75; Haworth, Simon32,76; Yousri, Noha A.77,78; Mitchell, Ruth E.32,79; Chai, Jin Fang80,81; Aadahl, Mette82,83; Bjerregaard, Anne A.82; Yao, Jie84; Manichaikul, Ani85; Hwu, Chii-Min86; Hung, Yi-Jen87; Warren, Helen R.88,89; Ramirez, Julia88,90,91; Bork-Jensen, Jette92; Karhus, Line L.82; Goel, Anuj61,93; Sabater-Lleal, Maria94,95; Noordam, Raymond96; Mauro, Pala97; Matteo, Floris97,98; McDaid, Aaron F.99,100; Marques-Vidal, Pedro101,102; Wielscher, Matthias103; Trompet, Stella96,104; Sattar, Naveed105; Mollehave, Line T.82; Munz, Matthias106,107,108,109,110; Zeng, Lingyao111,112; Huang, Jianfeng113,114,115; Yang, Bin113,114,115; Poveda, Alaitz116; Kurbasic, Azra116; Lamina, Claudia117,118; Forer, Lukas117,118; Scholz, Markus119,120; Galesloot, Tessel E.121; Bradfeld, Jonathan P.122; Ruotsalainen, Sanni E.35; Daw, EWarwick123; Zmuda, Joseph M.124; Mitchell, Jonathan S.125; Fuchsberger, Christian125; Christensen, Henry126; Brody, Jennifer A.127; Vazquez-Moreno, Miguel128; Feitosa, Mary F.123; Wojczynski, Mary K.123; Wang, Zhe129; Preuss, Michael H.129; Mangino, Massimo130,131; Christofdou, Paraskevi130; Verweij, Niek132; Benjamins, Jan W.132; Engmann, Jorgen133,134; Tsao, Noah L.135; Verma, Anurag4; Slieker, Roderick C.136,137; Lo, Ken Sin138; Zilhao, Nuno R.139; Le, Phuong140; Kleber, Marcus E.141,142; Delgado, Graciela E.141; Huo, Shaofeng143; Ikeda, Daisuke D.144; Iha, Hiroyuki144; Yang, Jian145,146,147; Liu, Jun148,149; Leonard, Hampton L.151,152; Marten, Jonathan153; Frank, Mirjam154; Schmidt, Borge154; Smyth, Laura J.155; Canadas-Garre, Marisa155,156,157,158; Wang, Chaolong159,160; Nakatochi, Masahiro161; Wong, Andrew162; Hutri-Kahonen, Nina163; Sim, Xueling80,81; Xia, Rui164; Huerta-Chagoya, Alicia165,166,167; Fernandez-Lopez, Juan Carlos168; Lyssenko, Valeriya116,169; Nongmaithem, Suraj S.171; Bayyana, Swati170,171; Stringham, Heather M.15; Irvin, Marguerite R.172; Oldmeadow, Christopher173; Kim, Han-Na174,175; Ryu, Seungho176,177; Timmers, Paul R. 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2022-12-27

10.1186/s13059-022-02837-1

GENOME BIOLOGY   影响因子和分区

1474-760X

["Background: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering downstream translational efforts such as drug target discovery.","Results: To expand our understanding of the underlying biological pathways and mechanisms controlling blood lipid levels, we leverage a large multi-ancestry meta-analysis (N=1,654,960) of blood lipids to prioritize putative causal genes for 2286 lipid associations using six gene prediction approaches. Using phenome-wide association (PheWAS) scans, we identify relationships of genetically predicted lipid levels to other diseases and conditions. We confirm known pleiotropic associations with cardiovascular phenotypes and determine novel associations, notably with cholelithiasis risk. We perform sex-stratified GWAS meta-analysis of lipid levels and show that 3-5% of autosomal lipid-associated loci demonstrate sex-biased effects. Finally, we report 21 novel lipid loci identified on the X chromosome. Many of the sex-biased autosomal and X chromosome lipid loci show pleiotropic associations with sex hormones, emphasizing the role of hormone regulation in lipid metabolism.","Conclusions: Taken together, our findings provide insights into the biological mechanisms through which associated variants lead to altered lipid levels and potentially cardiovascular disease risk."]

Cholesterol Lipids Genetics Genome-wide association study GWAS

SCI

英语

其他

NHLBI["R01HL127564","R01HL142711"] ; Wellcome Trust["201543/B/16/Z","202802/Z/16/Z"] ; European Union["HEALTH-F2-2013-601456","608765","786833"] ; TriPartite Immunometabolism Consortium [TrIC]-Novo Nordisk Foundation[NNF15CC0018486] ; American Diabetes Association Innovative and Clinical Translational Award[1-19-ICTS-068] ; Academy of Finland Center of Excellence in Complex Disease Genetics[312062] ; American Heart Association Postdoctoral Fellowship["15POST24470131","17POST33650016"] ; University of Bristol NIHR Biomedical Research Centre["BRC-1215-2001","MRC & WT 217065/Z/19/Z"] ; MRC Integrative Epidemiology Unit[MC_UU_00011] ; CRUK Integrative Cancer Epidemiology Programme[C18281/A19169] ; MRC[MC_UU_00011/1] ; American Heart Association[18CDA34110116] ; Miguel Servet contract from the ISCIII Spanish Health Institute[CP17/00142] ; British Heart Foundation (BHF)[FS/14/66/3129] ; null[Z01HG200362] ; null[R01HL142302] ; null[R01HL105756]

Biotechnology & Applied Microbiology ; Genetics & Heredity

Biotechnology & Applied Microbiology ; Genetics & Heredity

WOS:000927879600003

BMC

MOLECULAR BIOLOGY & GENETICS

Web of Science

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16.Univ Michigan, Dept Computat Med & Bioinformat, Ann Arbor, MI 48109 USA
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50.Univ Edinburgh, Usher Inst, 9 Little France Rd, Edinburgh EH16 4UX, Midlothian, Scotland
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58.Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Program Genet Epidemiol & Stat Genet, 677 Huntington Ave, Boston, MA 02115 USA
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88.Queen Mary Univ London, John Vane Sci Ctr, Barts & London Sch Med & Dent, William Harvey Res Inst, Charterhouse Sq, London, England
89.Queen Mary Univ London, NIHR Barts Cardiovasc Biomed Res Ctr, Barts & London Sch Med & Dent, London, England
90.Univ Zaragoza, Aragon Inst Engn Res, Zaragoza, Spain
91.Ctr Invest Biomed Red Bioingn Biomat & Nanomed, Zaragoza, Spain
92.Univ Copenhagen, Novo Nordisk Fdn Ctr Basic Metab Res, Fac Hlth & Med Sci, Copenhagen, Denmark
93.Univ Oxford, John Radclife Hosp, Radclife Dept Med, Div Cardiovasc Med, Oxford OX3 9DU, England
94.Inst Invest Biomed St Pau IIB ST PAU, Unit Genom Complex Dis, Barcelona, Spain
95.Karolinska Univ Hosp, Ctr Mol Med, Karolinska Inst, Dept Med, Stockholm, Sweden
96.Leiden Univ Med Ctr, Dept Internal Med, Sect Gerontol & Geriatr, Leiden, Netherlands
97.CNR, Ist Ric Genet & Biomed, Rome, Italy
98.Univ Sassari, Dipartimento Sci Biomed, Sardinia, Italy
99.Univ Lausanne, Univ Ctr Primary Care & Publ Hlth, Rte Berne 113, CH-1010 Lausanne, Switzerland
100.Swiss Inst Bioinformat, CH-1015 Lausanne, Switzerland
101.Lausanne Univ Hosp, Dept Med, Internal Med, Rue Bugnon 46, CH-1011 Lausanne, Switzerland
102.Univ Lausanne, Rue Bugnon 46, CH-1011 Lausanne, Switzerland
103.Imperial Coll London, MRC PHE Ctr Environm & Hlth, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England
104.Leiden Univ Med Ctr, Dept Cardiol, Leiden, Netherlands
105.BHF Glasgow Cardiovasc Res Ctr, Fac Med, Glasgow, Lanark, Scotland
106.Univ Lubeck, Univ Heart Ctr Lubeck, DZHK German Res Ctr Cardiovasc Res, Inst Cardiogenet,Partner Site Hamburg Lubeck Kiel, Lubeck, Germany
107.Charite Univ Med Berlin, Berlin, Germany
108.Free Univ Berlin, Berlin, Germany
109.Humboldt Univ, Berlin, Germany
110.Berlin Inst Hlth, Inst Dent & Craniofacial Sci, Dept Periodontol & Synopt Dent, Berlin, Germany
111.Tech Unive Munchen, Deutsch Herzzentrum Munchen, Klin Herz & Kreislauferkrankungen, Munich, Germany
112.Deutsch Zentrum Herz Kreislauf Forsch DZHK EV, Partner Site Munich Heart Alliance, Munich, Germany
113.Chinese Acad Med Sci & Peking Union Med Coll, Key Lab Cardiovasc Epidemiol, State Key Lab Cardiovasc Dis, Fuwai Hosp, Beijing 100037, Peoples R China
114.Chinese Acad Med Sci & Peking Union Med Coll, Dept Epidemiol, State Key Lab Cardiovasc Dis, Fuwai Hosp, Beijing 100037, Peoples R China
115.Chinese Acad Med Sci & Peking Union Med Coll, Natl Ctr Cardiovasc Dis, Beijing 100037, Peoples R China
116.Lund Univ, Lund Univ Diabet Ctr, Malmo, Sweden
117.Med Univ Innsbruck, Inst Genet Epidemiol, Dept Genet, Innsbruck, Austria
118.German Chron Kidney Dis Study, Berlin, Germany
119.Univ Leipzig, Inst Med Informat Stat & Epidemiol, Haertelstr 16-18, D-04107 Leipzig, Germany
120.Univ Leipzig, LIFE Res Ctr Civilizat Dis, Philipp Rosenthal Str 27, D-04103 Leipzig, Germany
121.Radboud Univ Nijmegen Med Ctr, Radboud Inst Hlth Sci, Nijmegen, Netherlands
122.Quantinuum Res LLC, Wayne, PA 19087 USA
123.Washington Univ, Dept Genet, Div Stat Genom, Sch Med, St Louis, MO USA
124.Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15261 USA
125.Inst Univ Lubeck, Inst Biomed, Eurac Res, Via Galvani 31, I-39100 Bolzano, Italy
126.Lillebaelt Hosp, Dept Clin Biochem, Vejle, Denmark
127.Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA 98101 USA
128.Hosp Especialidades Ctr Med La Raza, Ctr Med Nacl Siglo 21, Inst Mexicano Seguro Social, Unidad Invest Med Bioquim, Mexico City, DF, Mexico
129.Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA
130.Kings Coll London, Dept Twin Res & Genet Epidemiol, London SE1 7EH, England
131.Guys & St Thomas Fdn Trust, NIHR Biomed Res Ctr, London SE1 9RT, England
132.Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands
133.UCL, Inst Cardiovasc Sci, Gower St, London WC1E 6BT, England
134.UCL, Dept Epidemiol & Publ Hlth, 1-19 Torrington Pl, London WC1E 6BT, England
135.Univ Penn, Dept Surg, Philadelphia, PA 19104 USA
136.Amsterdam UMC, Dept Epidemiol & Data Sci, Amsterdam Publ Hlth Res Inst, NL-1081 HV Amsterdam, Netherlands
137.Leiden Univ Med Ctr, Dept Cell & Chem Biol, NL-2333 ZA Leiden, Netherlands
138.Univ Montreal, Montreal Heart Inst, 5000 Belanger St, Montreal, PQ H1T 1C8, Canada
139.Iceland Heart Assoc, IS-201 Kopavogur, Iceland
140.Univ Toronto Mississauga, Dept Anthropol, Mississauga, ON L5L 1C6, Canada
141.Heidelberg Univ, Med Fac Mannheim, Dept Med 5, D-68167 Mannheim, Germany
142.SYNLAB MVZ Humangenet Mannheim GmbH, D-68163 Mannheim, Germany
143.Univ Chinese Acad Sci, Chinese Acad Sci, Shanghai Inst Nutr & Hlth, Shanghai, Peoples R China
144.Otsuka Pharmaceut Co Ltd, Tokushima Res Inst, Biomed Technol Res Ctr, Tokushima, Japan
145.Westlake Univ, Sch Life Sci, Hangzhou 310024, Zhejiang, Peoples R China
146.Westlake Lab Life Sci & Biomed, Hangzhou 310024, Zhejiang, Peoples R China
147.Univ Queensland, Inst Mol Biosci, Brisbane, Qld 4072, Australia
148.Univ Oxford, Nufeld Dept Populat Hlth, Oxford, England
149.Univ Med Ctr Rotterdam, Dept Epidemiol, Erasmus MC, Rotterdam, Netherlands
150.Univ Surrey, Dept Clin & Expt Res, Sect Stat Multiom, Guildford, Surrey, England
151.NIA, Lab Neurogenet, NIH, Bethesda, MD 20892 USA
152.Data Tecn Int, Glen Echo, MD USA
153.Univ Edinburgh, Western Gen Hosp, Inst Genet & Canc, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
154.Univ Duisburg Essen, Inst Med Informat Biometry & Epidemiol, Essen, Germany
155.Queens Univ Belfast, Ctr Publ Hlth, Belfast, Antrim, North Ireland
156.Pfizer Univ Granada Andalusian Reg Govt, Ctr Genom & Oncol Res, Genom Oncol Area, GENYO, Granada, Spain
157.Hosp Univ Virgen Las Nieves, Hematol Dept, Granada, Spain
158.Inst Invest Biosanitaria Granada IbsGRANADA, Granada, Spain
159.Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Dept Epidemiol & Biostat, Wuhan, Peoples R China
160.Agcy Sci Technol & Res, Genome Inst Singapore, Singapore, Singapore
161.Nagoya Univ, Grad Sch Med, Dept Integrated Hlth Sci, Publ Hlth Informat Unit, Nagoya, Aichi 4618673, Japan
162.UCL, MRC Unit Lifelong Hlth & Ageing, 1-19 Torrington Pl, London WC1E 7HB, England
163.Tampere Univ, Fac Med & Hlth Technol, Tampere Ctr Skills Training & Simulat, Tampere, Finland
164.Univ Texas Hlth Sci Ctr Houston, Brown Fdn Inst Mol Med, McGovern Med Sch, Houston, TX 77030 USA
165.Inst Nacl Ciencias Med & Nutr Salvador Zubiran, CONACYT, Ciudad De Mexico, Mexico
166.Broad Inst MIT & Harvard, Program Metab & Med, Cambridge, MA USA
167.Univ Nacl Autonoma Mexico, Inst Invest Biomed, Dept Med Genom & Toxicol Ambiental, Mexico City 04510, DF, Mexico
168.Inst Nacl Med Genom, Dept Genom Computac, Mexico City, DF, Mexico
169.Univ Bergen, Ctr Diabet Res, Bergen, Norway
170.CSIR Ctr Cellular & Mol Biol, Genom Res Complex Dis GRC Grp, Hyderabad, Telangana, India
171.Acad Sci & Innovat Res AcSIR, New Delhi, India
172.Univ Alabama Birmingham, Sch Publ Hlth, Epidemiol, Birmingham, AL USA
173.Hunter Med Res Inst, Newcastle, NSW, Australia
174.Sungkyunkwan Univ, Kangbuk Samsung Hosp, Med Res Inst, Sch Med, Seoul 03181, South Korea
175.Sungkyunkwan Univ, Dept Clin Res Design & Evaluat, SAIHST, Seoul 06355, South Korea
176.Sungkyunkwan Univ, Kangbuk Samsung Hosp, Ctr Cohort Studies, Total Healthcare Ctr,Sch Med, Seoul 04514, South Korea
177.Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Occupat & Environm Med, Sch Med, Seoul 03181, South Korea
178.Univ Edinburgh, Ctr Global Hlth Res, Usher Inst, Teviot Pl, Edinburgh EH8 9AG, Midlothian, Scotland
179.Univ N Carolina, Thurston Arthrit Res Ctr, Chapel Hill, NC USA
180.Duke NUS Med Sch, Hlth Serv & Syst Res, Singapore 169857, Singapore
181.Univ Colorado, Dept Med, Div Biomed Informat & Personalized Med, Anschutz Med Campus, Aurora, CO 80045 USA
182.CSIR Inst Genom & Integrat Biol, Genom & Mol Med Unit, New Delhi 110020, India
183.Acad Sci & Innovat Res, CSIR Human Resource Dev Ctr, Ghaziabad, Uttar Pradesh, India
184.Radboud Univ Nijmegen, Dept Ophthalmol, Med Ctr, NL-6525 EX Nijmegen, Netherlands
185.Radboud Univ Nijmegen, Dept Human Genet, Med Ctr, NL-6525 EX Nijmegen, Netherlands
186.Vanderbilt Univ Sch Med, Vanderbilt Epidemiol Ctr, Div Epidemiol, Nashville, TN USA
187.Univ Calif San Francisco, Dept Pediat, Oakland, CA 94609 USA
188.Natl Ctr Global Hlth & Med, Tokyo 1628655, Japan
189.Univ N Carolina, Dept Genet, Chapel Hill, NC 27599 USA
190.Univ Massachusetts, Dept Biostat & Epidemiol, Amherst, MA 01003 USA
191.Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England
192.Glenfeld Hosp, NIHR Leicester Biomed Res Ctr, Leicester, Leics, England
193.Capital Med Univ, Beijing Tongren Hosp, Beijing Tongren Eye Ctr, Beijing Inst Ophthalmol, 17 Hougou Lane, Beijing 100005, Peoples R China
194.Capital Med Univ, Beijing Tongren Hosp, Beijing Tongren Eye Ctr, 1 Dong Jiao Min Xiang, Beijing 100730, Peoples R China
195.CNR, Inst Genet & Biophys Adriano Buzzati Traverso, Naples, Italy
196.IRCCS Neuromed, Pozzilli, Isernia, Italy
197.Washington Univ, Div Biostat, St Louis, MO 63110 USA
198.Rush Univ Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL USA
199.Rush Univ Med Ctr, Dept Neurol Sci, Chicago, IL USA
200.Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany
201.IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Trieste, Italy
202.German Inst Human Nutr Potsdam Rehbrucke, Dept Mol Epidemiol, Nuthetal, Germany
203.German Ctr Diabet Res DZD, Munich, Germany
204.Dasman Diabet Inst, Dept Genet & Bioinformat, Kuwait, Kuwait
205.Harokopio Univ Athens, Sch Hlth Sci & Educ, Dept Nutr & Dietet, Athens, Greece
206.UCL, Inst Hlth Informat, Dept Clin Epidemiol, London, England
207.Med Univ Graz, Dept Neurol, Clin Div Neurogeriatr, Graz, Austria
208.Med Univ Graz, Inst Med Informat Stat & Documentat, Graz, Austria
209.Massachusetts Gen Hosp Canc Ctr, Charlestown, MA 02129 USA
210.UOS Sassari, Natl Res Council Italy, Inst Genet & Biomed Res, Sassari, Italy
211.Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, NL-9700 RB Groningen, Netherlands
212.Univ Turku, Res Ctr Appl & Prevent Cardiovasc Med, Turku, Finland
213.Univ Turku, Ctr Populat Hlth Res, Turku, Finland
214.Turku Univ Hosp, Turku, Finland
215.Brigham & Womens Hosp, Sleep Med & Circadian Disorders, Boston, MA 02115 USA
216.Harvard Med Sch, Div Sleep Med, Boston, MA 02115 USA
217.Univ Utrecht, Univ Med Ctr Utrecht, Div Labs, Cent Diagnost Lab, Utrecht, Netherlands
218.NIA, Lab Epidemiol & Populat Sci, NIH, Baltimore, MD 20892 USA
219.Univ Houston Sugarland, Dept Engn Technol, Houston, TX USA
220.Univ Greifswald, Interfac Inst Genet & Funct Genom, Dept Funct Genom, Greifswald, Germany
221.Univ Med Greifswald, Greifswald, Germany
222.NHGRI, Ctr Res Genom & Global Hlth, NIH, 12 South Dr,Room 1025, Bethesda, MD 20892 USA
223.Oneomics Co Ltd 2F, Soonchunhyang Mirai Med Ctr, 173 Buheuyng Ro, Bucheon Si 14585, Gyeonggi Do, South Korea
224.Hosp Southern Jutland, Dept Clin Biochem & Immunol, Kresten Philipsens Vej 15, DK-6200 Aabenraa, Denmark
225.Lillebaelt Hosp, Dept Clin Biochem, Kolding, Denmark
226.Hallym Univ, Dept Biomed Sci, Chunchon 24252, Gangwon Do, South Korea
227.Univ Gothenburg, Sahlgrenska Acad, Ctr Bone & Arthrit Res, Inst Med, Gothenburg, Sweden
228.Univ Gothenburg, Sahlgrenska Acad, Bioinformat Core Facil, Gothenburg, Sweden
229.Univ Kiel, Inst Med Informat & Stat, Kiel, Germany
230.Helmholtz Zentrum Munchen, Inst Translat Genom, German Res Ctr Environm Hlth, Neuherberg, Germany
231.Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England
232.Univ Newcastle, Coll Hlth Med & Wellbeing, Sch Med & Publ Hlth, Newcastle, NSW 2308, Australia
233.Taichung Vet Gen Hosp, Ctr Geriatr & Gerontol, Dept Internal Med, Div Endocrinol & Metab, Taichung, Taiwan
234.Natl Yang Ming Univ, Sch Med, Taipei, Taiwan
235.Natl Def Med Ctr, Sch Med, Taipei, Taiwan
236.Taichung Vet Gen Hosp, Dept Internal Med, Div Endocrinol & Metab, Taichung, Taiwan
237.Natl Yang Ming Chiao Tung Univ, Sch Med, Dept Med, Taipei, Taiwan
238.Univ Laval, Dept Kinesiol, Quebec City, PQ, Canada
239.Fimlab Labs, Dept Clin Chem, Tampere 33520, Finland
240.Tampere Univ, Fac Med & Hlth Technol, Finnish Cardiovasc Res Ctr Tampere, Dept Clin Chem, Tampere 33014, Finland
241.Tampere Univ Hosp, Heart Ctr, Dept Cardiol, Tampere 33521, Finland
242.Tampere Univ, Fac Med & Hlth Technol, Finnish Cardiovasc Res Ctr Tampere, Dept Cardiol, Tampere 33014, Finland
243.Univ Queensland, Translat Res Inst, Diamantina Inst, Kent St, Brisbane, Qld 4102, Australia
244.Bornholms Hosp, Dept Med, Ronne, Denmark
245.Univ Alabama Birmingham, Ryals Sch Publ Hlth, Dept Epidemiol, Birmingham, AL USA
246.Univ Utrecht, Univ Med Ctr Utrecht, Div Heart & Lungs, Cardiol, Utrecht, Netherlands
247.Case Western Reserve Univ, Dept Populat & Quantitat Hlth Sci, Cleveland, OH 44106 USA
248.Stanford Univ, Dept Genet, Sch Med Stanford, Palo Alto, CA 94305 USA
249.Ohio State Univ, Div Endocrinol, Columbus, OH 43210 USA
250.Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA
251.George Washington Univ, Sch Med & Hlth Sci, Washington, DC 20037 USA
252.Peking Univ Hlth Sci Ctr, Sch Publ Hlth, Dept Epidemiol, Beijing, Peoples R China
253.Univ Hosp Leipzig, Inst Lab Med, Paul List Str 13-15, D-04103 Leipzig, Germany
254.NIH, Ctr Alzheimers & Related Dementias, Bethesda, MD USA
255.Data Tecn Int, Washington, DC USA
256.Turku Univ Hosp, Dept Clin Physiol & Nucl Med, Turku, Finland
257.Jichi Med Univ, Dept Environm & Prevent Med, Sch Med, Shimotsuke, Tochigi 3290498, Japan
258.Univ Edinburgh, Ctr Populat Hlth Sci, Usher Inst, Teviot Pl, Edinburgh EH8 9AG, Midlothian, Scotland
259.Shimane Univ, Dept Funct Pathol, Sch Med, Izumo, Shimane 6938501, Japan
260.Turku Univ Hosp, Dept Pediat & Adolescent Med, Turku, Finland
261.Univ Turku, Turku, Finland
262.Univ Turku, Dept Physiol, Turku, Finland
263.Univ Split, Sch Med, Soltanska 2, HR-21000 Split, Croatia
264.Univ Leipzig Med Ctr, Med Dept Endocrinol Nephrol Rheumatol 3, Liebigstr 18, D-04103 Leipzig, Germany
265.Harokopio Univ, Dept Nutr Dietet, Athens 17676, Greece
266.Osaka Univ, Dept Clin Gene Therapy, Grad Sch Med, Suita, Osaka 5650871, Japan
267.Osaka Univ, Dept Geriatr & Gen Med, Grad Sch Med, Suita, Osaka 5650871, Japan
268.Univ Utrecht, Univ Med Ctr Utrecht, Dept Vasc Surg, Div Surg Specialties, Utrecht, Netherlands
269.Yonsei Univ, Saevit Eye Hosp, Corneal Dystrophy Res Inst, Coll Med, Seoul 03722, South Korea
270.Univ Med Ctr Rotterdam, Dept Radiol & Nucl Med, Erasmus MC, Rotterdam, Netherlands
271.Univ Adolfo Ibanz, Latin Amer Brain Hlth BrainLat, Santiago, Chile
272.Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, NL-3584 CG Utrecht, Netherlands
273.Natl & Kapodistrian Univ Athens, Attikon Univ Hosp, Med Sch, Dept Cardiol 2, Athens, Greece
274.Univ Sydney, Ctr Vis Res, Dept Ophthalmol, Hawkesbury Rd, Sydney, NSW 2145, Australia
275.Univ Sydney, Westmead Inst, Hawkesbury Rd, Sydney, NSW 2145, Australia
276.Univ Tasmania, Sch Med, Menzies Inst Med Res, Liverpool St, Hobart, Tas 7000, Australia
277.Univ Melbourne, Ctr Eye Res Australia, Melbourne, Vic 3002, Australia
278.Tampere Univ Hosp, Dept Clin Physiol, Tampere 33521, Finland
279.Tampere Univ, Fac Med & Hlth Technol, Finnish Cardiovasc Res Ctr Tampere, Dept Clin Physiol, Tampere 33014, Finland
280.Inst Nutr & Funct Foods INAF, Ctr Nutr Sante & Soc NUTRISS, Quebec City, PQ, Canada
281.Pennington Biomed Res Ctr, Baton Rouge, LA 70808 USA
282.Univ Western Australia, Med Sch, Discipline Internal Med, Perth, WA, Australia
283.Univ Kiel, Inst Epidemiol, Kiel, Germany
284.Univ Kiel, Inst Clin Mol Biol, Kiel, Germany
285.Sahlgrens Univ Hosp, Dept Drug Treatment, Gothenburg, Sweden
286.Univ Gothenburg, Sahlgrenska Acad, Inst Med, Geriatr Med, Gothenburg, Sweden
287.Ewha Womans Univ, Dept Internal Med, Sch Med, Seoul, South Korea
288.Univ Pittsburgh, UPMC Hillman Canc Ctr, Div Canc Control & Populat Sci, Pittsburgh, PA 15232 USA
289.Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15232 USA
290.Natl Univ Singapore, Yong Loo Lin Sch Med, Hlth Longev Translat Res Programme, Singapore 117545, Singapore
291.ASTAR, Singapore Inst Clin Sci, Singapore 117609, Singapore
292.Kyung Hee Univ, Dept Endocrinol & Metab, Sch Med, Seoul 02447, South Korea
293.Univ Med Greifswald, Inst Community Med, Greifswald, Germany
294.NIA, Lab Epidemiol & Populat Sci, Intramural Res Program, NIH,Biomed Res Ctr, NIH 251 Bayview Blvd, Baltimore, MD 21224 USA
295.Algebra Univ Coll, Ilica 242, Zagreb, Croatia
296.Univ Turku, Paavo Nurmi Ctr, Dept Phys Act & Hlth, Sports & Exercise Med Unit, Turku, Finland
297.Univ Groningen, Univ Med Ctr Groningen, Interdisciplinary Ctr Psychopathol & Emot Regulat, NL-9700 RB Groningen, Netherlands
298.Natl Res Council Italy, Inst Mol Genet, Pavia, Italy
299.Med Univ Graz, Gottfried Schatz Res Ctr Cell Signaling Metab & A, Graz, Austria
300.Local Hlth Unit Toscana Ctr, Florence, Italy
301.Univ Potsdam, Inst Nutr Sci, Nuthetal, Germany
302.Univ Trieste, Dept Med Surg & Hlth Sci, Str Fiume 447, I-34149 Trieste, Italy
303.Traunstein Hosp, Dept Nephrol, Diabetol, Rheumatol, Traunstein, Germany
304.KfH Kidney Ctr Traunstein, Traunstein, Germany
305.Columbia Univ, Ctr Translat & Syst Neuroimmunol, Dept Neurol, Med Ctr, New York, NY USA
306.Natl & Kapodistrian Univ Athens, Med Sch, 75 M Assias St, Athens 11527, Greece
307.Dromokaiteio Psychiat Hosp, Athens 12461, Greece
308.Queen Mary Univ London, William Harvey Res Inst, London EC1M 6BQ, England
309.Heidelberg Univ, Med Fac Mannheim, Dept Ophthalmol, Kurzerufer 1, D-168167 Mannheim, Germany
310.Inst Mol & Clin Ophthalmol, Basel, Switzerland
311.Privatpraxis Prof Jonas & Dr Panda Jonas, Heidelberg, Germany
312.Univ Calif Los Angeles, David Gefen Sch Med, Dept Human Genet, Los Angeles, CA USA
313.Inst Invest Biomed UNAM, Unidad Biol Mol & Med Genom, Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Mexico City, DF, Mexico
314.Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Endocrinol & Metabol, Mexico City 14080, Mexico
315.Univ N Carolina, Gillings Sch Global Publ Hlth, Dept Nutr, Chapel Hill, NC 27599 USA
316.Univ N Carolina, Carolina Populat Ctr, Chapel Hill, NC 27516 USA
317.Univ San Carlos, USC Ofce Populat Studies Fdn, Cebu 6000, Philippines
318.Univ San Carlos, Dept Anthropol Sociol & Hist, Cebu 6000, Philippines
319.Univ Kelaniya, Fac Med, Dept Med, Ragama 11010, Sri Lanka
320.Univ Kelaniya, Fac Med, Dept Publ Hlth, Ragama 11010, Sri Lanka
321.Childrens Hosp Oakland Res Inst, Oakland, CA 94609 USA
322.Acad Sinica, Inst Biomed Sci, Taipei, Taiwan
323.Jawaharlal Nehru Univ, Sch Biotech Nol, Syst Genom Lab, New Delhi 110067, India
324.Univ Mississippi Med Ctr, Dept Med, Jackson, MS 39216 USA
325.Univ Mississippi Med Ctr, Dept Physiol & Biophys, Jackson, MS 39216 USA
326.Uppsala Univ, Dept Med Sci, Uppsala, Sweden
327.Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Paediat, Singapore, Singapore
328.Khoo Teck Puat Natl Univ, Natl Univ Hlth Syst, Childrens Med Inst, Singapore, Singapore
329.Univ N Carolina, Dept Med, Chapel Hill, NC USA
330.Univ N Carolina, Injury Prevent Res Ctr, Chapel Hill, NC USA
331.Univ N Carolina, Div Phys Therapy, Chapel Hill, NC USA
332.Vrije Univ Amsterdam, Dept Psychiat, Amsterdam UMC, Amsterdam, Netherlands
333.Ewha Womans Univ, Coll Med, Dept Biochem, Seoul 07804, South Korea
334.Univ Newcastle, Fac Hlth & Med, Callaghan, NSW, Australia
335.Washington Univ, Div Biostat, Sch Med, St Louis, MO USA
336.Univ South Carolina, Off Provost, Columbia, SC USA
337.Univ Utah, Dept Internal Med, Salt Lake City, UT 84132 USA
338.Newcastle Univ, Med Sch, Inst Cellular Med Diabet, Framlington Pl, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
339.Univ Helsinki, Helsinki Univ Hosp, Dept Med, POB 340, Helsinki 00029, Finland
340.Minerva Fdn, Biomed 2U,Tukholmankatu 8, Helsinki 00290, Finland
341.JSS Acad Higher Educ & Res, Mysuru, India
342.Massachusetts Gen Hosp, Diabet Unit, Boston, MA 02114 USA
343.Massachusetts Gen Hosp, Ctr Genom Med, Boston, MA 02114 USA
344.Harvard Med Sch, Boston, MA 02115 USA
345.Inst Nacl Salud Publ, Cuernavaca, Morelos, Mexico
346.Ctr Estudios Diabet, Cuernavaca, Morelos, Mexico
347.Inst Nacl Med Genom, Lab Inmunogen & Enfermedades Metab, Mexico City, DF, Mexico
348.Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Sch Publ Hlth, Houston, TX 77030 USA
349.Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore 119228, Singapore
350.Natl Univ Hlth Syst, Singapore 119228, Singapore
351.George Washington Univ, Milken Inst Sch Publ Hlth, Dept Exercise & Nutr Sci, Washington, DC 20052 USA
352.Kurume Univ, Sch Med, Kurume, Fukuoka 8300011, Japan
353.Merck Sharp & Dohme Corp, Genet, Kenilworth, NJ 07033 USA
354.Univ Dundee, Ninwells Hosp & Med Sch, Dundee DD1 9SY, Scotland
355.NIA, Intramural Res Program, 3001 S Hanover St, Baltimore, MD 21225 USA
356.Capital Med Univ, Beijing Tongren Hosp, Beijing Tongren Eye Ctr, Beijing Inst Ophthalmol, Beijing 100730, Peoples R China
357.Wenzhou Med Univ, Eye Hosp, Sch Ophthalmol & Optometry, Wenzhou 325027, Zhejiang, Peoples R China
358.SYNLAB Holding Deutschland GmbH, Synlab Acad, Mannheim, Germany
359.SYNLAB Holding Deutschland GmbH, Synlab Acad, Augsburg, Germany
360.Med Univ Graz, Clin Inst Med & Chem Lab Diagnost, Graz, Austria
361.Univ Iceland, Fac Med, IS-101 Reykjavik, Iceland
362.Leiden Univ Med Ctr, Dept Biomed Data Sci, Sect Mol Epidemiol, NL-2333 ZA Leiden, Netherlands
363.Amsterdam UMC, Dept Epidemiol & Data Sci, NL-1081 HV Amsterdam, Netherlands
364.Amsterdam Publ Hlth Res Inst, Amsterdam Cardiovasc Sci, NL-1081 HV Amsterdam, Netherlands
365.Amsterdam UMC, Dept Gen Practice, NL-1081 HV Amsterdam, Netherlands
366.Amsterdam Publ Hlth Res Inst, Hlth Behav & Chron Dis, NL-1081 HV Amsterdam, Netherlands
367.Corporal Michael Crescenz VA Med Ctr, Philadelphia, PA 19104 USA
368.Univ Essex, Inst Social & Econ Res, Wivenhoe Pk, Colchester CO4 3SQ, Essex, England
369.Icahn Sch Med Mt Sinai, Dept Environm Med & Publ Hlth, New York, NY 10029 USA
370.Univ Washington, Dept Hlth Syst & Populat Hlth, Seattle, WA 98195 USA
371.Univ Southern Denmark, Inst Reg Hlth Res, Odense, Denmark
372.Univ Southern Denmark, Danish Aging Res Ctr, Odense C, Denmark
373.Univ Helsinki, Fac Med, Publ Hlth, Helsinki, Finland
374.Broad Inst MIT & Harvard, Cambridge, MA 02142 USA
375.Childrens Hosp Philadelphia, Ctr Appl Genom, Philadelphia, PA 19104 USA
376.Univ Penn, Dept Pediat, Perelman Sch Med, Philadelphia, PA 19104 USA
377.Childrens Hosp Philadelphia, Div Human Genet, Philadelphia, PA 19104 USA
378.Southern Univ Sci & Technol, Sch Med, Shenzhen, Peoples R China
379.Netherlands Heart Inst, Utrecht, Netherlands
380.Massachusetts Gen Hosp, Dept Med, Div Cardiol, Boston, MA USA
381.Massachusetts Gen Hosp, Ctr Genom Med, Dept Med, Boston, MA USA
382.Harvard Med Sch, Dept Med, Boston, MA 02115 USA
383.Verve Therapeut, Cambridge, MA USA
384.Univ Oulu, Fac Med, Infrastruct Populat Studies, Northern Finland Birth Cohorts, Oulu, Finland
385.Univ Oulu, Fac Med, Ctr Life Course Hlth Res, Oulu, Finland
386.Univ Oulu, Bioctr Oulu, Oulu, Finland
387.Italian Natl Council Res IRGB CNR, Inst Genet & Biomed Res, Cagliari, Italy
388.Univ Sassari, Sassari, Italy
389.Leiden Univ Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands
390.Leiden Univ Med Ctr, Dept Publ Hlth & Primary Care, Leiden, Netherlands
391.Leiden Univ Med Ctr, Dept Internal Med, Div Endocrinol, Leiden, Netherlands
392.Leiden Univ Med Ctr, Einthoven Lab Expt Vasc Med, Leiden, Netherlands
393.Leiden Univ Med Ctr, Dept Human Genet, Leiden, Netherlands
394.St Georges Univ London, Populat Hlth Res Inst, London SW17 0RE, England
395.Imperial Coll London, Natl Heart & Lung Inst, London W12 0NN, England
396.Imperial Coll London, Sch Publ Hlth, London W12 7RH, England
397.Natl Taiwan Univ Hosp, Dept Internal Med, 7 Chung Shan South Rd, Taipei, Taiwan
398.Univ Oxford, Churchill Hosp, OCDEM, Oxford OX3 7LE, England
399.Churchill Hosp, NIHR Oxford Biomed Res Ctr, Oxford, England
400.Singapore Natl Eye Ctr, Singapore Eye Res Inst, Ocular Epidemiol, Singapore 168751, Singapore
401.Duke NUS Med Sch, Ophthalmol & Visual Sci Acad Clin Program Eye ACP, Singapore 169857, Singapore
402.Singapore Natl Eye Ctr, Singapore Eye Res Inst, Data Sci, Singapore 168751, Singapore
403.Univ Exeter, Med Sch, Exeter EX2 5DW, Devon, England
404.Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
405.NHLBI, Framingham Heart Study, US Natl Inst Hlth, Bethesda, MD USA
406.Mashhad Univ Med Sci, Sch Med, Dept Genet, Mashhad, Razavi Khorasan, Iran
407.Chinese Natl Human Genome Ctr Shanghai, Dept Genet, Shanghai MOST Key Lab Hlth & Dis Genom, Shanghai 201203, Peoples R China
408.Charite, Computat Med, Berlin Inst Hlth, Berlin, Germany
409.Tech Univ Munich TUM, Munich, Germany
410.TUM Sch Med, Klinikum Rechts Isar, Munich, Germany
411.Univ Eastern Finland, Inst Clin Med, Internal Med, Kuopio, Finland
412.Kuopio Univ Hosp, Kuopio, Finland
413.Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USA
414.Stanford Univ, Stanford Diabet Res Ctr, Stanford, CA 94305 USA
415.Regeneron Pharmaceut, Tarrytown, NY USA
416.Nanyang Technol Univ, Lee Kong Chian Sch Med, Singapore 308232, Singapore
417.Imperial Coll London, Imperial Coll Healthcare NHS Trust, London W12 0HS, England
418.Imperial Coll Healthcare NHS Trust, London W12 0HS, England
419.Imperial Coll London, MRC PHE Ctr Environm & Hlth, London W2 1PG, England
420.Univ Witwatersrand, Sch Elect & Informat Engn, Johannesburg, South Africa
421.Univ Illinois, Inst Minor Hlth Res, Coll Med, Chicago, IL USA
422.Harvard TH Chan Sch Publ Hlth, Dept Biostat, 677 Huntington Ave, Boston, MA 02115 USA
423.QIMR Berghofer Med Res Inst, 300 Herston Rd, Brisbane, Qld 4006, Australia
424.Faisalabad Inst Cardiol, Faislabad, Pakistan
425.Columbia Univ, Dept Med, Irving Med Ctr, New York, NY USA
426.Columbia Univ, Dept Cardiol, Irving Med Ctr, New York, NY USA
427.Univ Oxford, Big Data Inst, Oxford OX3 7LF, England
428.Oxford Univ Hosp, Natl Inst Hlth Res, Oxford Biomed Res Ctr, Oxford, England
429.Univ Aberdeen, Aberdeen Ctr Hlth Data Sci, Sch Med Med Sci & Nutr, 1 042 Polwarth Bldg, Aberdeen AB25 2ZD, Scotland
430.Univ Dundee, Ninewells Hosp & Med Sch, Div Populat Hlth & Genom, Dundee DD1 9SY, Scotland
431.Geisinger Hlth, Dept Populat Hlth Sci, Danville, PA 17822 USA
432.Kings Coll London, Fac Life Sci & Med, Sch Basic & Med Biosci, London, England
433.Vanderbilt Univ Sch Med, Dept Biomed Informat, Nashville, TN USA
434.Univ Washington, Dept Med Med Genet, Washington, DC USA
435.Univ Washington, Dept Genome Sci, Washington, DC USA
436.Cincinnati Childrens Hosp Med Ctr CCHMC, Ctr Autoimmune Genom & Etiol, Cincinnati, OH USA
437.Northwestern Univ, Feinberg Sch Med, Dept Med, Div Endocrinol, Chicago, IL 60618 USA
438.Northwestern Univ, Dept Anthropol, Evanston, IL 60208 USA
439.Norwegian Univ Sci & Technol, HUNT Res Ctr, Dept Publ Hlth & Nursing, NTNU, N-7600 Levanger, Norway
440.Trondheim Reg & Univ Hosp, Dept Res, St Olavs Hosp, Trondheim, Norway
441.Trondheim Reg & Univ Hosp, Dept Endocrinol, St Olavs Hosp, Trondheim, Norway
442.RIKEN Ctr Integrat Med Sci, Yokohama, Kanagawa, Japan
443.Univ Tokyo, Grad Sch Frontier Sci, Dept Computat Biol & Med Sci, Lab Complex Trait Genom, Tokyo, Japan
444.RIKEN Ctr Integrat Med Sci, Lab Syst Genet, Yokohama, Kanagawa, Japan
445.Univ Tokyo, Grad Sch Med, Dept Genome Informat, Tokyo, Japan
446.Univ Tokyo, Inst Med Sci, Div Mol Pathol, Tokyo, Japan
447.Univ Iceland, Fac Med, IS-102 Reykjavik, Iceland
448.VA Boston Healthcare Syst, Boston, MA USA
449.VA Informat & Comp Infrastruct, VA Salt Lake City Hlth Care Syst, Salt Lake City, UT USA
450.Univ Massachusetts, Boston, MA USA
451.Stanford Univ, Sch Med, Cardiovasc Inst, Stanford, CA USA
452.Corporal Michael J Crescenz VA Med Ctr, Philadelphia, PA USA
453.Univ Penn, Dept Med, Perelman Sch Med, Philadelphia, PA 19104 USA
454.Brigham Womens Hosp, Dept Med, Boston, MA USA
455.Emory Univ, Sch Med, Div Cardiol, Atlanta, GA 30322 USA
456.Harvard Med Sch, Dept Pediat, Boston, MA 02115 USA
457.Harvard Med Sch, Dept Genet, Boston, MA 02115 USA
458.Univ Manchester, Ctr Genet & Genom Versus Arthrit, Ctr Musculoskeletal Res, Div Musculoskeletal & Dermatol Sci, Manchester, Lancs, England
459.Harvard Med Sch, Massachusetts Gen Hosp, Cardiol Div, Boston, MA USA
460.Harvard Med Sch, Massachusetts Gen Hosp, Dept Med, Boston, MA USA
461.Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA
462.King Abdulaziz Univ, Princess Al Jawhara Al Brahim Ctr Excellence Res, Jeddah, Saudi Arabia
463.Univ Michigan, Dept Human Genet, Ann Arbor, MI 48109 USA

Kanoni, Stavroula,Graham, Sarah E.,Wang, Yuxuan,et al. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis[J]. GENOME BIOLOGY,2022,23(1).

Kanoni, Stavroula.,Graham, Sarah E..,Wang, Yuxuan.,Surakka, Ida.,Ramdas, Shweta.,...&Demirkan, Ayse.(2022).Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.GENOME BIOLOGY,23(1).

Kanoni, Stavroula,et al."Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis".GENOME BIOLOGY 23.1(2022).