中文版 | English
题名

Dual ph and oxygen luminescent nanosensors for extracellular metabolism monitoring

作者
通讯作者Yang, Cheng
发表日期
2019
ISSN
1526-7547
会议录名称
卷号
40
页码
184
会议地点
Seattle, WA, United states
出版者
摘要
Statement of Purpose: Glycolysis and oxidative phosphorylation are the two principal pathways in cell metabolism. Measurements of acidic metabolites and consumption of oxygen in culture medium caused by cell metabolism and respiration are significant for evaluating glycolysis and oxidative phosphorylation. Abnormal glycolysis and oxidative phosphorylation are related to various diseases, such as diabetes, Alzheimer’s disease and cancers. Therefore, developing dual pH and oxygen nanosensors is crucial for cell metabolism understanding, high-throughput analysis and diseases diagnosis. However, dual pH and oxygen optical sensors developed in previous studies are less sensitive and show lower quantum efficiency. Herein, we prepared amphiphilic graft copolymer-based dual luminescent pH and oxygen nanosensors with high sensitivity and quantum efficiency in extracellular cell metabolism monitoring.
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学校署名
第一 ; 通讯
收录类别
EI入藏号
20192006911654
EI主题词
Cells ; Cytology ; Diagnosis ; Efficiency ; Luminescence ; Nanosensors ; Oxygen ; Pathology ; Phosphorylation ; Quantum efficiency
EI分类号
Biological Materials and Tissue Engineering:461.2 ; Medicine and Pharmacology:461.6 ; Light/Optics:741.1 ; Nanotechnology:761 ; Chemical Reactions:802.2 ; Chemical Products Generally:804 ; Production Engineering:913.1 ; Quantum Theory; Quantum Mechanics:931.4 ; Solid State Physics:933
来源库
EV Compendex
成果类型会议论文
条目标识符http://sustech.caswiz.com/handle/2SGJ60CL/50936
专题工学院_材料科学与工程系
作者单位
1.Department of Materials Science and Engineering, Southern University of Science and Technology, No 1088 Xueyuan Road, Xili, Nanshan District, Shenzhen; Guangdong; 518055, China
2.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Avenida da Universidade, Taipa; Macau
第一作者单位材料科学与工程系
通讯作者单位材料科学与工程系
第一作者的第一单位材料科学与工程系
推荐引用方式
GB/T 7714
Yang, Cheng,Pan, Tingting,Chen, Meiwan,et al. Dual ph and oxygen luminescent nanosensors for extracellular metabolism monitoring[C]:Society for Biomaterials,2019:184.
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