题名 | Dual ph and oxygen luminescent nanosensors for extracellular metabolism monitoring |
作者 | |
通讯作者 | Yang, Cheng |
发表日期 | 2019
|
ISSN | 1526-7547
|
会议录名称 | |
卷号 | 40
|
页码 | 184
|
会议地点 | Seattle, WA, United states
|
出版者 | |
摘要 | Statement of Purpose: Glycolysis and oxidative phosphorylation are the two principal pathways in cell metabolism. Measurements of acidic metabolites and consumption of oxygen in culture medium caused by cell metabolism and respiration are significant for evaluating glycolysis and oxidative phosphorylation. Abnormal glycolysis and oxidative phosphorylation are related to various diseases, such as diabetes, Alzheimer’s disease and cancers. Therefore, developing dual pH and oxygen nanosensors is crucial for cell metabolism understanding, high-throughput analysis and diseases diagnosis. However, dual pH and oxygen optical sensors developed in previous studies are less sensitive and show lower quantum efficiency. Herein, we prepared amphiphilic graft copolymer-based dual luminescent pH and oxygen nanosensors with high sensitivity and quantum efficiency in extracellular cell metabolism monitoring. © 2019 Omnipress - All rights reserved. |
学校署名 | 第一
; 通讯
|
收录类别 | |
EI入藏号 | 20192006911654
|
EI主题词 | Cells
; Cytology
; Diagnosis
; Efficiency
; Luminescence
; Nanosensors
; Oxygen
; Pathology
; Phosphorylation
; Quantum efficiency
|
EI分类号 | Biological Materials and Tissue Engineering:461.2
; Medicine and Pharmacology:461.6
; Light/Optics:741.1
; Nanotechnology:761
; Chemical Reactions:802.2
; Chemical Products Generally:804
; Production Engineering:913.1
; Quantum Theory; Quantum Mechanics:931.4
; Solid State Physics:933
|
来源库 | EV Compendex
|
成果类型 | 会议论文 |
条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/50936 |
专题 | 工学院_材料科学与工程系 |
作者单位 | 1.Department of Materials Science and Engineering, Southern University of Science and Technology, No 1088 Xueyuan Road, Xili, Nanshan District, Shenzhen; Guangdong; 518055, China 2.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Avenida da Universidade, Taipa; Macau |
第一作者单位 | 材料科学与工程系 |
通讯作者单位 | 材料科学与工程系 |
第一作者的第一单位 | 材料科学与工程系 |
推荐引用方式 GB/T 7714 |
Yang, Cheng,Pan, Tingting,Chen, Meiwan,et al. Dual ph and oxygen luminescent nanosensors for extracellular metabolism monitoring[C]:Society for Biomaterials,2019:184.
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条目包含的文件 | 条目无相关文件。 |
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