Breast Cancer Marker Detection Based on Fiber Ring Laser with Lasso Structure

Jie Hu1; Liyang Shao1; Yang Ran2; Weihao Lin1; Fang Zhao1; Yuhui Liu1; Junhui Sun3; Huanhuan Liu1; Jinna Chen1; Perry Ping Shum1

10.1109/ACP55869.2022.10088785

2022

Asia Communications and Photonics Conference (ACP) / International Conference on Information Photonics and Optical Communications (IPOC)

2162-108X

978-1-6654-8156-4

2022 Asia Communications and Photonics Conference (ACP)

1934-1938

5-8 Nov. 2022

Shenzhen, China

345 E 47TH ST, NEW YORK, NY 10017 USA

IEEE

A lasso shaped fiber biosensor with optical fiber ring laser demodulation method was proposed for the specific detection of CEACAM5 - a kind of cancer marker protein. The laser signal held a narrow linewidth of 0.02 nm (3dB bandwidth) and high signal-to-noise ratio (SNR) of similar to 40 dB, enabling a good RI detection ability of 167 nm/RIU. Functionalization of the fiber laser was realized to detect a kind of cancer biomarker-CEACAM5. The limit of detection (LOD) could reach 28 ng/mL. This sensing device can be extended to other biological monitoring and has great potential as in situ biomedical monitoring devices that can be mass-produced.

Biosensor fiber laser lasso shape

第一

英语

CPCI-S

Department of Natural Resources of Guangdong Province[GDNRC[2022]]

Engineering ; Optics ; Telecommunications

Engineering, Electrical & Electronic ; Optics ; Telecommunications

WOS:001000552100499

IEEE

1.Department of Electrical and Electronic Engineering, College of Engineering, Southern University of Science and Technology, Shenzhen, China
2.Institute of Photonics Technology, Jinan University, Guangzhou, China
3.School of Innovation and Entrepreneurship, Southern University of Science and Technology, Shenzhen, China

Jie Hu,Liyang Shao,Yang Ran,et al. Breast Cancer Marker Detection Based on Fiber Ring Laser with Lasso Structure[C]. 345 E 47TH ST, NEW YORK, NY 10017 USA:IEEE,2022:1934-1938.