| 题名 | Facile access to chiral gamma-butyrolactones via rhodium-catalysed asymmetric hydrogenation of gamma-butenolides and gamma-hydroxybutenolides |
| 作者 | |
| 通讯作者 | Lang, Qiwei; Chen, Gen-Qiang; Zhang, Xumu |
| 发表日期 | 2023-04-01
|
| DOI | |
| 发表期刊 | |
| ISSN | 2041-6520
|
| EISSN | 2041-6539
|
| 卷号 | 14期号:18页码:4888-4892 |
| 摘要 | The highly efficient Rh/ZhaoPhos-catalysed asymmetric hydrogenation of ?-butenolides and ?-hydroxybutenolides was successfully developed. This protocol provides an efficient and practical approach to the synthesis of various chiral ?-butyrolactones, which are synthetically valuable building blocks of diverse natural products and therapeutic substances, with excellent results (up to >99% conversion and 99% ee). Further follow-up transformations have been revealed to accomplish creative and efficient synthetic routes for several enantiomerically enriched drugs via this catalytic methodology. |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 重要成果 | NI论文
|
| 学校署名 | 第一
; 通讯
|
| 资助项目 | Shenzhen Science and Technology Innovation Committee[JCYJ20210324104202007]
; Stable Support Plan Program of the Shenzhen Natural Science Fund[20200925161222002]
; Key-Area Research and Development Program of Guangdong Province[2020B010188001]
; Innovative Team of Universities in Guangdong Province[2020KCXTD016]
; National Natural Science Foundation of China[22171129]
; Guangdong Basic and Applied Basic Research Foundation[2022B1515020055]
|
| WOS研究方向 | Chemistry
|
| WOS类目 | Chemistry, Multidisciplinary
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| WOS记录号 | WOS:000973719000001
|
| 出版者 | |
| EI入藏号 | 20231714007651
|
| EI分类号 | Chemical Reactions:802.2
|
| 来源库 | Web of Science
|
| 引用统计 |
被引频次[WOS]：5
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/536119 |
| 专题 | 理学院_化学系 前沿与交叉科学研究院 深圳格拉布斯研究院 |
| 作者单位 | 1.Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Dept Chem, Shenzhen 518000, Peoples R China 2.Southern Univ Sci & Technol, Med Pingshan, Shenzhen 518000, Peoples R China 3.Southern Univ Sci & Technol, Acad Adv Interdisciplinary Studies, Shenzhen 518000, Peoples R China |
| 第一作者单位 | 化学系; 深圳格拉布斯研究院; 南方科技大学 |
| 通讯作者单位 | 化学系; 深圳格拉布斯研究院; 南方科技大学; 前沿与交叉科学研究院 |
| 第一作者的第一单位 | 化学系; 深圳格拉布斯研究院 |
| 推荐引用方式 GB/T 7714 |
Zhou, Yuxuan,Guo, Siyuan,Huang, Qiyuan,et al. Facile access to chiral gamma-butyrolactones via rhodium-catalysed asymmetric hydrogenation of gamma-butenolides and gamma-hydroxybutenolides[J]. CHEMICAL SCIENCE,2023,14(18):4888-4892.
|
| APA |
Zhou, Yuxuan,Guo, Siyuan,Huang, Qiyuan,Lang, Qiwei,Chen, Gen-Qiang,&Zhang, Xumu.(2023).Facile access to chiral gamma-butyrolactones via rhodium-catalysed asymmetric hydrogenation of gamma-butenolides and gamma-hydroxybutenolides.CHEMICAL SCIENCE,14(18),4888-4892.
|
| MLA |
Zhou, Yuxuan,et al."Facile access to chiral gamma-butyrolactones via rhodium-catalysed asymmetric hydrogenation of gamma-butenolides and gamma-hydroxybutenolides".CHEMICAL SCIENCE 14.18(2023):4888-4892.
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| 条目包含的文件 | 条目无相关文件。 | |||||
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