Recent developments and controversies in therapeutic hypothermia after cardiopulmonary resuscitation

Li, Peijuan1,5,6; Sun, Zhangping1,5,6; Tian, Tian1,5,6; Yu, Dongping2; Tian, Hui3; Gong, Ping1,4,7,8

2023-02-01

10.1016/j.ajem.2022.11.002

AMERICAN JOURNAL OF EMERGENCY MEDICINE   影响因子和分区

0735-6757

1532-8171

Therapeutic hypothermia was recommended as the only neuroprotective treatment in comatose patients after return of spontaneous circulation (ROSC). With new evidence suggesting a similar neuroprotective effect of 36 degrees C and 33 degrees C, the term "therapeutic hypothermia" was substituted by "targeted temperature management" in 2011, which in turn was replaced by the term "temperature control" in 2022 because of new evidence of the similar effects of target normothermia and 33 degrees C. However, there is no clear consensus on the efficacy of ther-apeutic hypothermia. In this article, we provide an overview of the recent evidence from basic and clinical research related to therapeutic hypothermia and re-evaluate its application as a post-ROSC neuroprotective in-tervention in clinical settings.(c) 2022 Elsevier Inc. All rights reserved.

Cardiopulmonary resuscitation Return of spontaneous circulation Therapeutic hypothermia Targeted temperature management Temperature control

SCI

英语

通讯

Shenzhen Key Medical Discipline Construction Fund[SZXK046] ; National Nature Science Foundation of China, China[81571869]

Emergency Medicine

Emergency Medicine

WOS:000974990900001

W B SAUNDERS CO-ELSEVIER INC

CLINICAL MEDICINE

Web of Science

1.Dalian Med Univ, Affiliated Hosp 1, Dept Emergency, Dalian, Liaoning, Peoples R China
2.Dalian Med Univ, Affiliated Hosp 2, Dept Emergency, Dalian, Liaoning, Peoples R China
3.Dalian Municipal Cent Hosp, Dept Emergency, Dalian, Liaoning, Peoples R China
4.Jinan Univ, Shenzhen Peoples Hosp, Clin Med Coll 2, Dept Emergency, Shenzhen, Guangdong, Peoples R China
5.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen, Guangdong, Peoples R China
6.Dalian Med Univ, Dalian, Liaoning, Peoples R China
7.Jinan Univ, Clin Med Coll 2, Shenzhen People's Hosp, Dept Emergency, 1017 Dongmen North Rd, Shenzhen 518020, Guangdong, Peoples R China
8.Southern Univ Sci & Technol, Affiliated Hosp 1, 1017 Dongmen North Rd, Shenzhen 518020, Guangdong, Peoples R China

Li, Peijuan,Sun, Zhangping,Tian, Tian,et al. Recent developments and controversies in therapeutic hypothermia after cardiopulmonary resuscitation[J]. AMERICAN JOURNAL OF EMERGENCY MEDICINE,2023,64.

Li, Peijuan,Sun, Zhangping,Tian, Tian,Yu, Dongping,Tian, Hui,&Gong, Ping.(2023).Recent developments and controversies in therapeutic hypothermia after cardiopulmonary resuscitation.AMERICAN JOURNAL OF EMERGENCY MEDICINE,64.

Li, Peijuan,et al."Recent developments and controversies in therapeutic hypothermia after cardiopulmonary resuscitation".AMERICAN JOURNAL OF EMERGENCY MEDICINE 64(2023).